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Ebf gene function is required for coupling neuronal differentiation and cell cycle exit
Helix-loop-helix transcription factors of the Ebf/Olf1 family have previously been implicated in the control of neurogenesis in the central nervous system in both Xenopus laevis and the mouse, butExpand
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The chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 gene
CHD8 is a chromatin remodeling ATPase of the SNF2 family. We found that depletion of CHD8 impairs cell proliferation. In order to identify CHD8 target genes, we performed a transcriptomic analysis ofExpand
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SUMO association with repressor complexes, emerging routes for transcriptional control.
Covalent attachment of the small ubiquitin-like modifier (SUMO) to proteins constitutes a posttranslational modification intensely studied during the last decade. From the many proteins that serve asExpand
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A two‐component signal transduction system involved in nickel sensing in the cyanobacterium Synechocystis sp. PCC 6803
In the cyanobacterium Synechocystis sp. PCC 6803, genes for Ni2+, Co2+, and Zn2+ resistance are grouped in a 12 kb gene cluster. The nrsBACD operon is composed of four genes, which encode proteinsExpand
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Association of bromodomain BET proteins with chromatin requires dimerization through the conserved motif B
Summary BET (bromodomain and extra terminal domain) family proteins are unique among bromodomain-containing proteins in that they not only associate with acetylated chromatin in interphase, but alsoExpand
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Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.
Myogenic regulatory factors such as MyoD and Myf5 lie at the core of vertebrate muscle differentiation. However, E-boxes, the cognate binding sites for these transcription factors, are not restrictedExpand
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Pleiotrophin antagonizes Brd2 during neuronal differentiation
ABSTRACT Bromodomain-containing protein 2 (Brd2) is a BET family chromatin adaptor required for expression of cell-cycle-associated genes and therefore involved in cell cycle progression. Brd2 isExpand
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The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators
Covalent attachment of small ubiquitin‐like modifier (SUMO) to proteins regulates many processes in the eukaryotic cell. This reaction is similar to ubiquitination and usually requires an E3 ligaseExpand
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Thiol-based redox modulation of a cyanobacterial eukaryotic-type serine/threonine kinase required for oxidative stress tolerance.
AIMS Protein phosphorylation is a principal signaling mechanism that mediates regulation of enzymatic activities, modulation of gene expression, and adaptation to environmental changes. RecentExpand
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Furfural production from Eucalyptus globulus: Optimizing by using neural fuzzy models
Abstract Samples of Eucalyptus globulus were subjected to isothermal autohydrolysis (temperature: 220–250 °C and isothermal residence time 0–60 min). The effect of the R 0 factor on the sugar yieldExpand
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