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A network of fast-spiking cells in the neocortex connected by electrical synapses
Encoding of information in the cortex is thought to depend on synchronous firing of cortical neurons. Inhibitory neurons are known to be critical in the coordination of cortical activity, but howExpand
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Electrical and chemical synapses among parvalbumin fast-spiking GABAergic interneurons in adult mouse neocortex
Networks of γ-aminobutyric acid (GABA)ergic interneurons connected via electrical and chemical synapses are thought to play an important role in detecting and promoting synchronous activity in theExpand
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Frequency-dependent synaptic depression and the balance of excitation and inhibition in the neocortex
The stability of cortical neuron activity in vivo suggests that the firing rates of both excitatory and inhibitory neurons are dynamically adjusted. Using dual recordings from excitatory pyramidalExpand
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Electrical synapses between Gaba-Releasing interneurons
Although gap junctions were first demonstrated in the mammalian brain about 30 years ago, the distribution and role of electrical synapses have remained elusive. A series of recent reports hasExpand
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Synaptic Interactions of Late-Spiking Neocortical Neurons in Layer 1
Layer 1 of the neocortex is an important zone in which synaptic integration of inputs originating from a variety of cerebral regions is thought to take place. Layer 1 does not contain pyramidalExpand
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Electrical synapses define networks of neocortical GABAergic neurons
Recent work using paired recording has provided a direct demonstration of functional electrical synapses between neocortical neurons of both juvenile and adult animals. Electrical synapses have beenExpand
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Spike Transmission and Synchrony Detection in Networks of GABAergic Interneurons
The temporal pattern and relative timing of action potentials among neocortical neurons may carry important information. However, how cortical circuits detect or generate coherent activity remainsExpand
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Electrical Coupling among Irregular-Spiking GABAergic Interneurons Expressing Cannabinoid Receptors
Anatomical studies have shown that the G-protein-coupled cannabinoid receptor-1 (CB1) is selectively expressed in a subset of GABAergic interneurons. It has been proposed that these cells regulateExpand
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Properties of GABAA Receptors Underlying Inhibitory Synaptic Currents in Neocortical Pyramidal Neurons
Rapid applications of GABA (from 10 μm to 10 mm) to outside-out patches were used to study the role that the kinetic properties of GABAA receptors play in determining the time course of IPSCs inExpand
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Cannabinoid sensitivity and synaptic properties of 2 GABAergic networks in the neocortex.
Distinct networks of gamma-aminobutyric acidergic interneurons connected by electrical synapses can promote different patterns of activity in the neocortex. Cannabinoids affect memory and cognitionExpand
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