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1 alpha, 25-dihydroxyvitamin D3 and all-trans-retinoic acid inhibit the growth of a lung cancer cell line.
The secosteroid 1 alpha, 25-dihydroxyvitamin D3 (calcitriol) and retinoic acid are the major biologically active metabolites of vitamins D and A, respectively. Their antitumor activity has been… Expand
Effect of chronic tobacco smoke exposure on the function of alveolar macrophages in mice.
- Y. Higashimoto, Y. Fukuchi, +7 authors E. Sudo
- Respiration; international review of thoracic…
We evaluated the effect of chronic tobacco smoke exposure on the function of the alveolar macrophage (AM) in mice. Tumor necrosis factor-alpha production of the AM triggered by lipopolysaccharides… Expand
Idiopathic acute eosinophilic pneumonia.
A previously healthy young man presented with acute respiratory distress, high fever and bilateral ground-glass appearance on chest radiograph. Bronchoalveolar lavage analysis demonstrated… Expand
Stimulatory Effect of 1α,25-Dihydroxyvitamin D3 on Mouse Alveolar Macrophage Tumor Necrosis Factor-α Production in vitro: Involvement of Protein Kinase C and Ca2+/Calmodulin-Dependent Kinase
1α,25-Dihydroxyvitamin D3 [1α,25(OH)2D3, calcitriol] has been shown to modulate the immune function of peripheral monocytes and peritoneal macrophages. However, its ef
Effect of aging on plasma 1,5-anhydroglucitol levels in humans and rats.
- M. Funasako, M. Taniji, +7 authors Y. Sakagami
- Diabetes research and clinical practice
- 1 August 1994
Since normal reference values change with age in some clinical parameters, we measured the plasma levels of 1,5-anhydroglucitol (AG), a new marker of glycemic control in diabetes mellitus, in healthy… Expand
[A case of chronic hypersensitivity pneumonitis due to long term exposure to toluene diisocyanate].
A 55-year-old paint sprayer, who had been working with paint containing toluence diisocyanate since age 20, was admitted to our hospital with a complaint of exertional dyspnea. Physical examination… Expand
[Influence of age on mouse pulmonary alveolar macrophage clonal growth].
- Y. Higashimoto, M. Ohata, +6 authors Y. Fukuchi
- Nihon Ronen Igakkai zasshi. Japanese journal of…
Although monocyte influx has been suggested as the primary source of pulmonary alveolar macrophages (AM), increasing evidence from recent studies has indicated that AM may be sustained through a… Expand
[Effects of aerosol oxitropium bromide and fenoterol on maximal exercise capacity in chronic obstructive pulmonary disease and their correlation with air flow during exercise and with parameters of…
- T. Suruda, H. Nakamura, +5 authors M. Ohata
- Nihon Kyobu Shikkan Gakkai zasshi
- 25 September 1993
To examine the effects of bronchodilators on maximal exercise capacity and their correlation with airflow during exercise in patients with chronic obstructive pulmonary disease (COPD), we conducted a… Expand
[A case of primary intrapulmonary benign schwannoma].
- Y. Higashimoto, M. Ohata, +5 authors A. Ooshima
- Nihon Kyobu Shikkan Gakkai zasshi
- 25 March 1991
A case of primary intrapulmonary schwannoma was described. A 72-year-old man was admitted to our hospital because of dry cough. A chest radiograph showed partial atelectasis of the middle lobe, but… Expand
Areal bone mineral density and bone phosphatase activities in experimental diabetes mellitus
- M. Funasako, M. Taniji, +7 authors M. Ohata
- Journal of Bone and Mineral Metabolism
- 1 September 1996
To investigate the mechanisms of osteopenia in diabetes mellitus induced experimentally in mice, we measured the bone mineral content, expressed as the bone mineral density per surface area (areal… Expand