• Publications
  • Influence
Molecular Cloning and Expression of a Novel β-1,6-N-Acetylglucosaminyltransferase That Forms Core 2, Core 4, and I Branches*
Mucin-type O-glycans are classified according to their core structures. Among them, cores 2 and 4 are important for having N-acetyllactosamine side chains, which can be further modified to expressExpand
  • 193
  • 15
A cDNA clone used to study mRNA inducible in human tonsillar lymphocytes by a tumor promoter.
A cDNA clone inducible by either a tumor promoter, 12-o-tetradecanoyl phorbol-13-acetate (TPA), or a T-cell mitogen, phytohemagglutinin (PHA), was isolated from a cDNA library constructed from theExpand
  • 112
  • 6
Control of O-Glycan Branch Formation
Core 2 O-glycan branching catalyzed by UDP-N-acetyl-α-d-glucosamine: acceptor β1,6-N-acetylglucosaminyltransferases (β6GlcNAc-Ts) is an important step in mucin-type biosynthesis. Core 2 complex-typeExpand
  • 101
  • 6
A short, novel promoter sequence confers the expression of human leukosialin, a major sialoglycoprotein on leukocytes.
  • S. Kudo, M. Fukuda
  • Biology, Medicine
  • The Journal of biological chemistry
  • 5 May 1991
Human leukosialin (CD43) is a major sialoglycoprotein expressed on leukocytes and platelets. In order to investigate the transcriptional regulation of this gene, we have isolated a genomic DNA of 12Expand
  • 24
  • 4
  • PDF
Transcriptional activation of human leukosialin (CD43) gene by Sp1 through binding to a GGGTGG motif.
Human leukosialin (CD43) is expressed on the surface of hematopoietic cells in cell-type specific and differentiation-stage-specific manners. Previously we found that the sequence from -53 to -40 wasExpand
  • 28
  • 4
Molecular Cloning and Expression of a Novel Humantrans-Golgi Network Glycoprotein, TGN51, That Contains Multiple Tyrosine-containing Motifs*
Previously, it has been shown that glycoproteins with ∼130-kDa molecular mass react with antisera from patients with renal vasculitis (Kain, R., Matsui, K., Exner, M., Binder, S., Schaffner, G.,Expand
  • 34
  • 4
Transcriptional Properties of Mammalian Elongin A and Its Role in Stress Response*
Background: Transcriptional elongation is a rate-limiting step in activation of stress response genes. Results: Optimal expression of stress response regulator ATF3 requires the elongation activityExpand
  • 15
  • 3
Structural organization of glycophorin A and B genes: glycophorin B gene evolved by homologous recombination at Alu repeat sequences.
  • S. Kudo, M. Fukuda
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 June 1989
Glycophorins A (GPA) and B (GPB) are two major sialoglycoproteins of the human erythrocyte membrane. Here we present a comparison of the genomic structures of GPA and GPB developed by analyzing DNAExpand
  • 101
  • 2
  • PDF
Expression of a Specific Glycosyltransferase Enzyme Regulates T Cell Death Mediated by Galectin-1*
Galectin-1 induces apoptosis of immature thymocytes and activated T cells, suggesting that galectin-1 regulates cell death in the thymus during selection and in the periphery following an immuneExpand
  • 132
  • 2
  • PDF
Tissue-specific Transcriptional Regulation of Human Leukosialin (CD43) Gene Is Achieved by DNA Methylation (*)
  • S. Kudo, M. Fukuda
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2 June 1995
The expression of human leukosialin (CD43), a major sialoglycoprotein on the surface of hematopoietic cells, is regulated in cell lineage-specific as well as differentiation stage-specific manners.Expand
  • 69
  • 2