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White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging
Objective: To investigate the extent and the nature of white matter tissue damage of patients with Alzheimer's disease using diffusion tensor magnetic resonance imaging (DT-MRI). Background: AlthoughExpand
EEG coherence in Alzheimer's disease.
EEG coherence can be used to evaluate the functionality of cortical connections and to get information about the synchronization of the regional cortical activity. We studied EEG coherence inExpand
MCI conversion to dementia and the APOE genotype
Objectives: To investigate whether the combination of fluoro-2-deoxy-d-glucose (FDG) PET measures with the APOE genotype would improve prediction of the conversion from mild cognitive impairmentExpand
Association of early‐onset Alzheimer's disease with an interleukin‐1α gene polymorphism
Overexpression of the pluripotent cytokine interleukin‐1 (IL‐1) by microglial cells correlates with formation of neuritic β‐amyloid plaques in Alzheimer's disease (AD). We evaluated polymorphisms inExpand
Heterogeneity of brain glucose metabolism in mild cognitive impairment and clinical progression to Alzheimer disease.
BACKGROUND Subjects with amnesic mild cognitive impairment (aMCI) may include patients at high risk for progression to Alzheimer disease (AD) and a population with different underlying pathologicExpand
The contribution of voxel-based morphometry in staging patients with mild cognitive impairment
Objective: To assess whether different patterns of regional gray matter loss in patients with mild cognitive impairment (MCI) are associated with different risks of conversion to Alzheimer diseaseExpand
The Frontal Assessment Battery Does Not Differentiate Frontotemporal Dementia from Alzheimer’s Disease
Background: An early differentiation of Alzheimer’s disease (AD) from frontotemporal dementia (FTD) is important, since these conditions are essentially different regarding prognosis andExpand
Glucose metabolism and serotonin receptors in the frontotemporal lobe degeneration
In patients with the frontal variant of frontotemporal lobar degeneration (fv‐FTLD), behavioral abnormalities may vary from apathy with motor slowness (apathetic form) to disinhibition with agitationExpand
A diffusion tensor MRI study of patients with MCI and AD with a 2-year clinical follow-up
Objective The authors assessed whether brain changes detected by diffusion tensor (DT) MRI can improve the understanding of structural damage in Alzheimer's disease (AD) and are associated withExpand
Expression of the transcription factor Sp1 and its regulatory hsa-miR-29b in peripheral blood mononuclear cells from patients with Alzheimer's disease.
Altered gene expression occurs in central nervous system disorders, including Alzheimer's disease (AD). Transcription factor Sp1 (specificity protein 1) can regulate the expression of severalExpand