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Genome-wide association studies of female reproduction in tropically adapted beef cattle.
Very few of the significant markers for female reproduction traits for the Brahman and Tropical Composite breeds were located in the same chromosomal regions, however, fatness and BW traits as well as serum IGF1 concentration were found to be associated with similar genome regions within and between breeds. Expand
Association weight matrix for the genetic dissection of puberty in beef cattle
The association weight matrix results recapitulate the known biology of puberty, captured experimentally validated binding sites, and identified candidate genes and gene–gene interactions for further investigation. Expand
A single nucleotide polymorphism-derived regulatory gene network underlying puberty in 2 tropical breeds of beef cattle.
This work aimed at developing and studying gene networks underlying cattle puberty, and employed network connectivity and centrality parameters along with a regulatory impact factor metric to identify the key transcription factors responsible for the molecular regulation of puberty. Expand
Evidence for pleiotropism and recent selection in the PLAG1 region in Australian Beef cattle.
The C allele appears to mark a mutation that has been selected almost to fixation in the B. taurus breeds studied here and introduced into Brahman cattle during grading up and selected to a frequency of 0.52 despite its negative effects on fertility. Expand
Genome‐wide association study for inhibin, luteinizing hormone, insulin‐like growth factor 1, testicular size and semen traits in bovine species
Genome‐wide association studies were carried out to identify genomic regions and genes associated with reproductive traits measured during the pubertal development of Tropical Composite bulls, providing evidence contributing to gene function annotation in the context of male fertility. Expand
Candidate Genes Associated with Testicular Development, Sperm Quality, and Hormone Levels of Inhibin, Luteinizing Hormone, and Insulin-Like Growth Factor 1 in Brahman Bulls1
ABSTRACT Bull fertility is an important target for genetic improvement, and early prediction using genetic markers is therefore a goal for livestock breeding. We performed genome-wide associationExpand
Prospecting major genes in dairy buffaloes
A genome-wide association study (GWAS) and gene network analysis carried out in buffaloes identified SNP with significant associations and suggested candidate genes that were specific to each trait and also genes with pleiotropic effect, associated to multiple traits. Expand
Bovine gene polymorphisms related to fat deposition and meat tenderness
The results showed no association between the genotypes and traits studied, but a genetic group effect on these traits was found; the genetic background remains relevant for fat deposition and meat tenderness, but the gene markers developed for Bos taurus may be insufficient for Bos indicus. Expand
Real-time PCR genotyping and frequency of the myostatin F94L mutation in beef cattle breeds.
Two real-time PCR assays are developed, employing high-resolution melt and allele-specific analysis to accurately genotype the F94L mutation in cattle, indicating the significant potential for this mutation to improve retail yield in Australian beef cattle. Expand
Finding genes for economically important traits: Brahman cattle puberty
The results of a genome-wide association study using the BovineSNP50 chip suggest that the genes located in that region of BTA 14 play a role in pubertal development in Brahman cattle. Expand