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Systematic discovery of multicomponent therapeutics
- A. Borisy, P. Elliott, C. Keith
- Biology, MedicineProceedings of the National Academy of Sciences…
- 10 June 2003
TLDR
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
- Nobutaka Kato, Eamon Comer, S. Schreiber
- Biology, ChemistryNature
- 20 October 2016
TLDR
Stereoselective Synthesis of over Two Million Compounds Having Structural Features Both Reminiscent of Natural Products and Compatible with Miniaturized Cell-Based Assays
- Derek S. Tan, M. Foley, M. Shair, S. Schreiber
- Chemistry, Biology
- 8 August 1998
TLDR
Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies
- C. Dockendorff, M. Nagiec, S. Schreiber
- Chemistry, BiologyACS medicinal chemistry letters
- 30 August 2012
TLDR
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
- Channing Yu, Aristotle M. Mannan, T. Golub
- BiologyNature Biotechnology
- 12 January 2016
TLDR
Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action
- J. B. Steinman, C. Santarossa, T. Kapoor
- Biology, ChemistryeLife
- 19 May 2017
TLDR
Selective Phenylimidazole-based Inhibitors of the Mycobacterium tuberculosis Proteasome.
- Wenhu Zhan, H. Hsu, G. Lin
- Biology, ChemistryJournal of medicinal chemistry
- 27 September 2019
TLDR
Loss of immunoreactivity for human calmodulin-like protein is an early event in breast cancer development.
- M. S. Rogers, M. Foley, E. Strehler
- Biology, MedicineNeoplasia
- 1 August 1999
TLDR
Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression
- M. Nagiec, Adam P. Skepner, M. Palmer
- BiologyPloS one
- 26 March 2015
TLDR
Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.
- M. Tremblay, M. Nevalainen, J. Adams
- Chemistry, BiologyJournal of medicinal chemistry
- 9 October 2008
TLDR
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