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The FUR (ferric uptake regulator) superfamily: diversity and versatility of key transcriptional regulators.
  • M. Fillat
  • Biology, Medicine
  • Archives of biochemistry and biophysics
  • 15 March 2014
Control of metal homeostasis is essential for life in all kingdoms. In most prokaryotic organisms the FUR (ferric uptake regulator) family of transcriptional regulators is involved in the regulationExpand
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Iron availability affects mcyD expression and microcystin-LR synthesis in Microcystis aeruginosa PCC7806.
Microcystins are toxins produced by cyanobacteria that entail serious health and environmental problems. They are cyclic heptapeptides synthesized via a mixed polyketide synthase/non-ribosomalExpand
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Functional Replacement of Ferredoxin by a Cyanobacterial Flavodoxin in Tobacco Confers Broad-Range Stress Tolerance[W]
Chloroplast ferredoxin (Fd) plays a pivotal role in plant cell metabolism by delivering reducing equivalents to various essential oxidoreductive pathways. Fd levels decrease under adverseExpand
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2‐oxoglutarate enhances NtcA binding activity to promoter regions of the microcystin synthesis gene cluster
The binding affinity of NtcA towards promoter regions of the microcystin gene cluster from Microcystis aeruginosa PCC 7806 has been analyzed by band‐shift assay (EMSA). The key nitrogenExpand
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Identification of a furA cis antisense RNA in the cyanobacterium Anabaena sp. PCC 7120.
Ferric uptake regulation (Fur) proteins are prokaryotic transcriptional regulators that integrate iron metabolism with several environmental stress responses. The regulatory network that governs FurExpand
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Constitutive and nitrogen‐regulated promoters of the petH gene encoding ferredoxin:NADP+ reductase in the heterocyst‐forming cyanobacterium Anabaena sp
Determination of the putative transcription start points of the petH gene encoding ferredoxin:NADP+ reductase in the heterocyst‐forming cyanobacteria Anabaena sp. PCC 7119 and PCC 7120 showed thatExpand
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Fur from Microcystis aeruginosa binds in vitro promoter regions of the microcystin biosynthesis gene cluster.
Promoter regions of the mcy operon from Microcystis aeruginosa PCC7806, which is responsible for microcystin synthesis in this organism, exhibit sequences that are similar to the sequences recognizedExpand
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Identification of a Ferric uptake regulator from Microcystis aeruginosa PCC7806.
Ferric uptake regulator (Fur) proteins are widely recognized as repressors that in many prokaryotes regulate a large number of genes involved in iron homeostasis and oxidative stress response. In ourExpand
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Microcystin-LR synthesis as response to nitrogen: transcriptional analysis of the mcyD gene in Microcystis aeruginosa PCC7806
The influence of environmental factors on microcystin production by toxic cyanobacteria has been extensively studied. However, the effect of nitrogen on the synthesis of this toxin remains unclearExpand
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Phosphate deficiency (N/P 40:1) induces mcyD transcription and microcystin synthesis in Microcystis aeruginosa PCC7806.
A real-time RT-PCR analysis of the transcriptional response to phosphate availability of the mcyD gene and microcystin-LR synthesis in Microcystis aeruginosa PCC7806 revealed that no significantExpand
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