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Exercise training and nutritional supplementation for physical frailty in very elderly people.
High-intensity resistance exercise training is a feasible and effective means of counteracting muscle weakness and physical frailty in very elderly people, in contrast to multi-nutrient supplementation without concomitant exercise, which does not reduce muscle weakness orPhysical frailty.
High-intensity strength training in nonagenarians. Effects on skeletal muscle.
It is concluded that high-resistance weight training leads to significant gains in muscle strength, size, and functional mobility among frail residents of nursing homes up to 96 years of age.
Exercise and physical activity for older adults
Regular exercise improves health status and contributes to an increase in life expectancy, and involvement in regular exercise can also provide a number of psychological benefits related to preserved cognitive function, alleviation of depression symptoms.
Aging of skeletal muscle: a 12-yr longitudinal study.
- W. Frontera, V. Hughes, R. Fielding, M. Fiatarone, W. Evans, R. Roubenoff
- MedicineJournal of applied physiology
- 1 April 2000
It is suggested that a quantitative loss in muscle CSA is a major contributor to the decrease in muscle strength seen with advancing age and accounts for 90% of the variability in strength at T2.
Leg extensor power and functional performance in very old men and women.
- E. Bassey, M. Fiatarone, E. O'Neill, M. Kelly, W. Evans, L. Lipsitz
- MedicineClinical science
- 1 March 1992
Measurement of leg extensor power in frail elderly people may prove useful in focusing effective rehabilitation programmes because of the relation within the group between age and any of the variables measured.
Effects of high-intensity strength training on multiple risk factors for osteoporotic fractures. A randomized controlled trial.
High-intensity strength training exercises are an effective and feasible means to preserve bone density while improving muscle mass, strength, and balance in postmenopausal women.
Acute phase response in exercise. III. Neutrophil and IL-1 beta accumulation in skeletal muscle.
- R. Fielding, T. Manfredi, W. Ding, M. Fiatarone, W. Evans, J. Cannon
- Medicine, BiologyAmerican Journal of Physiology
- 1 July 1993
After eccentric exercise ultrastructural damage to skeletal muscle is associated with neutrophil infiltration and muscle IL-1 beta accumulation and positively correlated to intracellular Z-band damage.
A randomized controlled trial of progressive resistance training in depressed elders.
- N. Singh, K. Clements, M. Fiatarone
- Psychology, MedicineThe journals of gerontology. Series A, Biological…
PRT is an effective antidepressant in depressed elders, while also improving strength, morale, and quality of life.
Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance.
It is demonstrated that chronic exercise training without changes in body composition improves peripheral insulin action in subjects with impaired glucose tolerance, and improved oral glucose tolerance was observed.
Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis.
Urinary 3-methylhistidine excretion correlated with mononuclear cell secretion of both IL-1 beta and prostaglandin E2, supporting the concept that these mon onuclear cell products contribute to the regulation of muscle proteolysis.