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Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome
Down syndrome (DS) is a genetic pathology characterized by intellectual disability and brain hypotrophy. Widespread neurogenesis impairment characterizes the fetal and neonatal DS brain, stronglyExpand
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Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis
Remyelination in the adult central nervous system has been demonstrated in different experimental models of demyelinating diseases. However, there is no clear evidence that remyelination occurs inExpand
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Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats.
Clinical symptoms in multiple sclerosis include cognitive dysfunction. Difficulties in learning and remembering new information represent the most common cognitive deficit and are associated with aExpand
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Neural stem cells and cholinergic neurons: Regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor
Degenerative diseases represent a severe problem because of the very limited repair capability of the nervous system. To test the potential of using stem cells in the adult central nervous system asExpand
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Adenosine A1 receptor down‐regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats
Pregnant rats were treated daily with 1 g/L of caffeine or theophylline in their drinking water during pregnancy and the effect of these methylxanthines on adenosine A1 receptor was assayed usingExpand
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Course of cognitive decline in hematopoietic stem cell transplantation: a within-subjects design.
This study examined the course of clinically significant cognitive change in hematopoietic stem cell transplant (HSCT), using a Reliable Change Index (RCI). Neuropsychological evaluations wereExpand
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Redescription of Antarctophthirus microchir (Anoplura: Echinophthiriidae) from the South American Sea Lion, Otaria flavescens, from Patagonia, Argentina
Abstract Antarctophthirus microchir was originally described from Phocarctos hookeri on the basis of 1 female and 1 male only. We redescribe adults and describe, for the first time, the 3 nymphalExpand
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Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease.
Chronic disabilities in multiple sclerosis are believed to be due to neuron damage and degeneration, which follow remyelination failure. Due to the presence of numerous oligodendrocyte precursorsExpand
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Phoretic mites of the six-spined engraver beetle, Ips sexdentatus (Böerner, 1776) (Coleoptera, Scolytinae), on Pinus halepensis in Slovenia
In September 2009, specimens of Ips sexdentatus were captured using black cross vane traps in an old stand of Pinus halepensis Miller at Dekani in the submediterranean ecological region of Slovenia.Expand
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Thyroid hormone participates in the regulation of neural stem cells and oligodendrocyte precursor cells in the central nervous system of adult rat.
Oligodendrocyte development and myelination are under thyroid hormone control. In this study we analysed the effects of chronic manipulation of thyroid status on the expression of a wide spectrum ofExpand
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