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Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation
A pattern of ancestral allele frequency distributions that reflects variation in population dynamics among geographic regions is observed and is consistent with the hypothesis of a serial founder effect with a single origin in sub-Saharan Africa. Expand
Genetic Structure of Human Populations
General agreement of genetic and predefined populations suggests that self-reported ancestry can facilitate assessments of epidemiological risks but does not obviate the need to use genetic information in genetic association studies. Expand
Niche Construction: The Neglected Process in Evolution
This book extends evolutionary theory by formally including niche construction and ecological inheritance as additional evolutionary processes, and demonstrates how the theory can resolve long-standing problems in ecology, particularly by advancing the sorely needed synthesis of ecology and evolution. Expand
Cultural transmission and evolution: a quantitative approach.
A mathematical theory of the non-genetic transmission of cultural traits is developed that provides a framework for future investigations in quantitative social and anthropological science and concludes that cultural transmission is an essential factor in the study of cultural change. Expand
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa.
It is found that heterozygosities in the globally distributed populations of the data set are best explained by an expansion originating in Africa and that no geographic origin outside of Africa accounts as well for the observed patterns of genetic diversity. Expand
A Human Genome Diversity Cell Line Panel
A resource of 1064 cultured lymphoblastoid cell lines (LCLs) ([1][1]) from individuals in different world populations and corresponding milligram quantities of DNA is deposited at the Foundation JeanExpand
An evaluation of genetic distances for use with microsatellite loci.
A genetic distance based on the stepwise mutation model that includes allelic repeat score is developed and found that for phylogenetic reconstruction of taxa that are sufficiently diverged, this new distance is preferable. Expand
Genetic absolute dating based on microsatellites and the origin of modern humans.
It is estimated that the deepest split in the human phylogeny occurred about 156,000 years ago, and the new distance is independent of population size and therefore allows direct estimation of divergence times if the mutation rate is known. Expand
Local dispersal promotes biodiversity in a real-life game of rock–paper–scissors
It is found that diversity is rapidly lost in the experimental community when dispersal and interaction occur over relatively large spatial scales, whereas all populations coexist when ecological processes are localized. Expand
Signals of recent positive selection in a worldwide sample of human populations.
Analysis of recent selection in a global sample of 53 populations, using genotype data from the Human Genome Diversity-CEPH Panel, suggests that there has been selection on loci involved in susceptibility to type II diabetes. Expand