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Pharmacokinetics of drugs in pregnancy.
Pregnancy is a complex state where changes in maternal physiology have evolved to favor the development and growth of the placenta and the fetus. These adaptations may affect preexisting disease or… Expand
Clinical Therapeutics in Pregnancy
Most drugs are not tested for use during pregnancy, consequently, labeling, which may include information about fetal safety, includes nothing about dosing, efficacy, or maternal safety. Yet these… Expand
Placental maternal vascular malperfusion and adverse pregnancy outcomes in gestational diabetes mellitus.
INTRODUCTION Maternal vascular malperfusion (MVM) lesions represent hypoxic-ischemic damage to the placenta, and they are associated with adverse pregnancy outcomes. Women with gestational diabetes… Expand
Large-for-Gestational-Age Ultrasound Diagnosis and Risk for Cesarean Delivery in Women With Gestational Diabetes Mellitus
OBJECTIVE: To assess the accuracy of a large-for-gestational-age (LGA) ultrasound diagnosis and the subsequent risk for cesarean delivery associated with ultrasound diagnosis of LGA among women with… Expand
Adverse Outcomes and Potential Targets for Intervention in Gestational Diabetes and Obesity
- C. Scifres, M. Feghali, A. Althouse, S. Caritis, J. Catov
- Obstetrics and gynecology
- 1 August 2015
OBJECTIVE: To evaluate the association of obesity with pregnancy outcomes in women with gestational diabetes mellitus (GDM) and identify potentially modifiable risk factors for adverse outcomes in… Expand
Maternal prepregnancy obesity and cause-specific stillbirth.
- L. Bodnar, W. Parks, +7 authors H. Simhan
- The American journal of clinical nutrition
- 1 October 2015
BACKGROUND In high-income countries, maternal obesity is one of the most important modifiable causes of stillbirth, yet the pathways underpinning this association remain unclear. OBJECTIVE We… Expand
Asymmetric large for gestational age newborns in pregnancies complicated by diabetes mellitus: is maternal obesity a culprit?
- M. Feghali, J. Khoury, Julia Timofeev, D. Shveiky, R. Driggers, M. Miodovnik
- The journal of maternal-fetal & neonatal medicine…
- 1 January 2012
Objective: Evaluate the association between body mass index (BMI) and the delivery of an asymmetrically large for gestational age (A-LGA) newborn in women with diabetes. Methods: Retrospective… Expand
Early Pregnancy Diabetes Screening and Diagnosis: Prevalence, Rates of Abnormal Test Results, and Associated Factors.
- John F. Mission, J. Catov, T. Deihl, M. Feghali, C. Scifres
- Obstetrics and gynecology
- 1 November 2017
OBJECTIVE To evaluate the prevalence of early diabetes screening in pregnancy, rates of abnormal diabetes test results before 24 weeks of gestation, and factors associated with early diabetes… Expand
Ultrasound assessment of congenital fetal lung masses and neonatal respiratory outcomes
Fetal congenital lung masses generate concern for compromised postnatal respiratory function. Congenital pulmonary adenomatoid malformation volume ratio (CVR) has been used to predict the risk of… Expand
Asymmetric large-for-gestational-age infants of type 1 diabetic women: morbidity and abdominal growth.
- S. Bollepalli, L. Dolan, M. Miodovnik, M. Feghali, J. Khoury
- American journal of perinatology
- 11 March 2010
We sought to examine neonatal morbidity in four groups of offspring (asymmetric large for gestational age [LGA], symmetric LGA, asymmetric non-LGA, symmetric non-LGA) exposed in utero to maternal… Expand