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Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway
It is proposed that the SCN utilizes neuronal pathways to spread its time of the day message, not only to the pineal, but also to other organs, including the adrenal, utilizing the autonomic nervous system.
Molecular changes underlying reduced pineal melatonin levels in Alzheimer disease: alterations in preclinical and clinical stages.
- Ying‐Hui Wu, M. Feenstra, D. Swaab
- Biology, MedicineThe Journal of clinical endocrinology and…
- 1 December 2003
It is concluded that a dysfunction of noradrenergic regulation and the depletion of serotonin by increased monoamine oxidase A result in the loss of melatonin rhythm already in preclinical AD.
Reward-Predictive Cues Enhance Excitatory Synaptic Strength onto Midbrain Dopamine Neurons
In vivo voltammetry and in vitro patch-clamp electrophysiology show that both dopamine release to reward predictive cues and enhanced synaptic strength onto dopamine neurons develop over the course of cue-reward learning.
Rapid sampling of extracellular dopamine in the rat prefrontal cortex during food consumption, handling and exposure to novelty
Dopaminergic control of cognitive flexibility in humans and animals
Findings from animal and human studies that have investigated the involvement of striatal DA in cognitive flexibility may provide a better understanding of the role of dopaminergic dysfunction in cognitive inflexibility in psychiatric disorders, such as OCD.
Local Activation of Metabotropic Glutamate Receptors Inhibits the Handling‐Induced Increased Release of Dopamine in the Nucleus Accumbens but Not that of Dopamine or Noradrenaline in the Prefrontal…
It is concluded that metabotropic receptors in the nucleus accumbens are important for the control of activation of DA release in the Accumbens by physiological stimuli but that a similar mechanism is lacking in the prefrontal cortex.
Comparison of dopamine and noradrenaline release in mouse prefrontal cortex, striatum and hippocampus using microdialysis
Dopamine efflux in nucleus accumbens shell and core in response to appetitive classical conditioning
- J. J. Cheng, J. D. de Bruin, M. Feenstra
- Psychology, BiologyThe European journal of neuroscience
- 1 September 2003
Unlike previous conditioning paradigms involving either a more salient US or a more complex CS, the present paradigm, using normal reward pellets as US and a discrete auditory stimulus as CS, did not lead to differential responses in dopamine efflux in shell and core subregions of the nucleus accumbens.
Novelty-induced increase in dopamine release in the rat prefrontal cortex in vivo: inhibition by diazepam