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- Publications
- Influence
CathaCyc, a metabolic pathway database built from Catharanthus roseus RNA-Seq data.
- Alex Van Moerkercke, M. Fabris, +7 authors A. Goossens
- Biology, Medicine
- Plant & cell physiology
- 1 May 2013
The medicinal plant Madagascar periwinkle (Catharanthus roseus) synthesizes numerous terpenoid indole alkaloids (TIAs), such as the anticancer drugs vinblastine and vincristine. The TIA pathway… Expand
Cutting-Edge Issues in Celiac Disease and in Gluten Intolerance
- N. Bizzaro, R. Tozzoli, D. Villalta, M. Fabris, E. Tonutti
- Medicine
- Clinical Reviews in Allergy & Immunology
- 1 June 2012
Celiac disease (CD) is a gluten-dependent immune-mediated disease with a prevalence in the general population estimated between 0.3% and 1.2%. Large-scale epidemiological studies have shown that only… Expand
The transcription factor bZIP14 regulates the TCA cycle in the diatom Phaeodactylum tricornutum
- M. Matthijs, M. Fabris, +6 authors A. Goossens
- Biology, Medicine
- The EMBO journal
- 1 June 2017
Diatoms are amongst the most important marine microalgae in terms of biomass, but little is known concerning the molecular mechanisms that regulate their versatile metabolism. Here, the pennate… Expand
Emerging Technologies in Algal Biotechnology: Toward the Establishment of a Sustainable, Algae-Based Bioeconomy
- M. Fabris, Raffaela M Abbriano, +9 authors P. J. Ralph
- Medicine
- Frontiers in Plant Science
- 17 March 2020
Mankind has recognized the value of land plants as renewable sources of food, medicine, and materials for millennia. Throughout human history, agricultural methods were continuously modified and… Expand
Extrachromosomal genetic engineering of the marine diatom Phaeodactylum tricornutum enables the heterologous production of monoterpenoids.
Geraniol is a commercially-relevant plant-derived monoterpenoid that is a main component of rose essential oil and used as insect repellent. Geraniol is also a key intermediate compound in the… Expand
Metabolic Engineering Strategies in Diatoms Reveal Unique Phenotypes and Genetic Configurations With Implications for Algal Genetics and Synthetic Biology
- J. George, Tim Kahlke, Raffaela M Abbriano, Unnikrishnan Kuzhiumparambil, P. Ralph, M. Fabris
- Biology, Medicine
- Frontiers in Bioengineering and Biotechnology
- 5 June 2020
Diatoms are photosynthetic microeukaryotes that dominate phytoplankton populations and have increasing applicability in biotechnology. Uncovering their complex biology and elevating strains to… Expand
Enhancing diatom lipid production through metabolic engineering, first phases
- M. Matthijs, M. Fabris, Gino Baart, A. Goossens, W. Vyverman
- Chemistry
- 2012
The biological productiv ity o f marine heterokonts, and specifically diatoms, is one o f the major contributors to the marine foodweb. In growth lim iting conditions diatoms store energy and carbon… Expand
Differential expression of a model diatom in the early phases of lipid accumulation
- M. Matthijs, M. Fabris, Gino Baart, A. Goossens, W. Vyverman
- Chemistry
- 2013
Diatoms are unicellular algae that contribute tremendously to the primary production of aquatic ecosystems. Their main primary storage products are lipids. We work with the main model species for… Expand
Enhancing lipid production of Phaeodactylum tricornutum through metabolic engineering
- M. Matthijs, M. Fabris, Gino Baart, A. Goossens, Wim Vyverman
- Chemistry
- 2012
- 1
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The early nitrogen starvation response of the diatom Phaeodactylum tricornutum
- M. Matthijs, M. Fabris, +5 authors A. Goossens
- Chemistry
- 2014
In th is study we investigated the transcrip tom ic and metabolic response o f Phaeodactylum trico rnu tum to nitrogen starvation and other stresses during the firs t 24 hours. P. tr ico rnu tum is a… Expand