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Association of diabetic neuropathy with Na/K ATPase gene polymorphism

• Philippe Vague, D. Dufayet, Thierry Charles Coste, Christine Moriscot, M. F. Jannot, D Raccah
• Diabetologia
• 1997

Diabetes mellitus induces a decrease in Na/K ATpase activity in man and animals, and this decrease plays a role in the development of diabetic neuropathy. Na/K ATPase is encoded by various genes, of… (More)

Erythrocyte Na/K ATPase activity and diabetes: relationship with C-peptide level

• D. Dufayet De La Tour, D Raccah, M. F. Jannot, Thierry Charles Coste, Cécile Rougerie, Philippe Vague
• Diabetologia
• 1998

Erythrocyte Na/K ATPase activity is decreased in Type I diabetic patients; for Type II diabetic patients, literature data are controversial. Therefore, we have compared this enzymatic activity in 81… (More)

Relationship between neuropathy, hypertension and red blood cell Na/K ATPase in patients with insulin-dependent diabetes mellitus.

• M. F. Jannot, D Raccah, D Dufayet de la Tour, Thierry Charles Coste, J. Gouvernet, Philippe Vague
• Diabetes & metabolism
• 1999

Hypertension has been proposed as an independent risk factor for diabetic neuropathy. In insulin-dependent diabetic (IDDM) patients suffering from neuropathy, red blood cell (RBC) Na/K ATPase is… (More)

The effects ex vivo and in vitro of insulin and C-peptide on Na/K adenosine triphosphatase activity in red blood cell membranes of type 1 diabetic patients.

• A. Djemli-Shipkolye, P. Gallice, +4 authors Philippe Vague
• Metabolism: clinical and experimental
• 2000

The decrease in Na/K adenosine triphosphatase (ATPase) activity observed in several tissues of type 1 diabetic patients is thought to play a role in the development of long-term complications.… (More)

Diverging evolution of anti-GAD and anti-IA-2 antibodies in long-standing diabetes mellitus as a function of age at onset: no association with complications.

• Laurence Hermitte, Catherine Atlan-Gepner, +5 authors Bernard Vialettes
• Diabetic medicine : a journal of the British…
• 1998

Glutamic acid decarboxylase autoantibodies (GAD-A) and tyrosine phosphatase IA-2 autoantibodies (IA2-A) were measured in sera of 50 recently diagnosed (<6 wk, 33% younger than 15 yr), 19 short-term… (More)

Genetic and environmental regulation of Na/K adenosine triphosphatase activity in diabetic patients.

• M. F. Jannot, D Raccah, D Dufayet De La Tour, Thierry Charles Coste, Philippe Vague
• Metabolism: clinical and experimental
• 2002

Even if the pathogenesis of diabetic neuropathy is incompletely understood, an impaired Na/K adenosine triphosphatase (ATPase) activity has been involved in this pathogenesis. We previously showed… (More)

C-peptide, Na+,K+-ATPase, and Diabetes

• Philippe Vague, Thibault Coste, M. F. Jannot, D Raccah, Michel Tsimaratos
• Experimental diabesity research
• 2004

Na+,K(+)-ATPase is an ubiquitous membrane enzyme that allows the extrusion of three sodium ions from the cell and two potassium ions from the extracellular fluid. Its activity is decreased in many… (More)

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