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Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach
There is poor agreement on definitions of different phenotypes of preschool wheezing disorders. The present Task Force proposes to use the terms episodic (viral) wheeze to describe children whoExpand
International consensus on (ICON) pediatric asthma
Asthma is the most common chronic lower respiratory disease in childhood throughout the world. Several guidelines and/or consensus documents are available to support medical decisions on pediatricExpand
Recommendations for the assessment and management of cough in children
All children experience head colds and many consult their doctor because of associated coughing.1 Cough with colds remedies are among the most commonly used medications in children in WesternExpand
Chronic wet cough: Protracted bronchitis, chronic suppurative lung disease and bronchiectasis
The role of persistent and recurrent bacterial infection of the conducting airways (endobronchial infection) in the causation of chronic respiratory symptoms, particularly chronic wet cough, hasExpand
Getting to grips with 'dysfunctional breathing'.
Dysfunctional breathing (DB) is common, frequently unrecognised and responsible for a substantial burden of morbidity. Previously lack of clarity in the use of the term and the use of multiple termsExpand
Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection.
To study the cellular infiltrate that occurs within the airways of infants with respiratory syncytial virus bronchiolitis, samples of airways secretions were obtained by bronchial lavage from theExpand
Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a–mediated T reg expansion
Respiratory syncytial virus–bronchiolitis is a major independent risk factor for subsequent asthma, but the causal mechanisms remain obscure. We identified that transient plasmacytoid dendritic cellExpand
Flow early in the inspiratory manoeuvre affects the aerosol particle size distribution from a Turbuhaler.
Several in vitro and in vivo studies have emphasized the importance of generating a high inspiratory flow when using a dry powder inhaler. Little attention has been paid to the influence of theExpand
Outcomes in children treated for persistent bacterial bronchitis
Background: Persistent bacterial bronchitis (PBB) seems to be under-recognised and often misdiagnosed as asthma. In the absence of published data relating to the management and outcomes in thisExpand
Budesonide/formoterol in a single inhaler versus inhaled corticosteroids alone in the treatment of asthma
The aim of this study was to evaluate the efficacy (expressed as effect on lung function) and tolerability of Symbicort® (budesonide/formoterol in a single inhaler) in children with asthma.