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Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring
Natalizumab, a highly specific α4-integrin antagonist, is approved for treatment of patients with active relapsing-remitting multiple sclerosis (RRMS). It is generally recommended for individuals whoExpand
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Safety and tolerability of interferon beta-1b in pediatric multiple sclerosis
Background: Immunomodulatory therapies are widely used in adults with multiple sclerosis (MS) and safety and tolerability is well-established. Although at least 5% of all patients with MS experienceExpand
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Subacute Sclerosing Panencephalitis: Clinical and Magnetic Resonance Imaging Evaluation of 36 Patients
We studied 36 patients (24 males, 12 females), all of whom had definite subacute sclerosing panencephalitis with typical periodic complexes in their electroencephalograms and increased titers ofExpand
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Inflammatory/demyelinating central nervous system involvement in familial Mediterranean fever (FMF): coincidence or association?
Background and ObjectiveFamilial Mediterranean fever (FMF) is an inherited inflammatory disease characterized by recurrent febrile polyserositis. Central nervous system (CNS) involvement in FMF isExpand
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MRI in subacute sclerosing panencephalitis
Abstract Subacute sclerosing panencephalitis (SSPE) is a progressive, slow virus infection of the brain, caused by the measles virus, attacking children and young adults. We investigated 15 patientsExpand
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HLA-DR and -DQ associations with multiple sclerosis in Turkey.
The DRB, DQA, and DQB subregions of the major histocompatibility complex (MHC) were investigated by polymerase chain reaction and sequence-specific oligonucleotide probe hybridization (PCR/SSO) inExpand
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Prognostic implications of aquaporin-4 antibody status in neuromyelitis optica patients
Neuromyelitis optica (NMO) is an inflammatory/demyelinating disorder predominantly affecting the optic nerves and spinal cord. Recent findings showed an underlying humoral abnormality in NMO,Expand
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Enhanced IL-6 Production in Aquaporin-4 Antibody Positive Neuromyelitis Optica Patients
ABSTRACT Anti-aquaporin-4 (Aqp-4) antibody and complement system have emerged as major pathogenic factors in neuromyelitis optica (NMO). To test the significance of interleukin-6 (IL-6), anotherExpand
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Recurrent absence status epilepticus: clinical and EEG characteristics
In order to outline the clinical and EEG characteristics of recurrent absence status epilepticus (ASE), eight cases with more than two attacks of ASE were studied. Their current ages were between 13Expand
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Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort
JC virus (JCV) is an opportunistic virus known to cause progressive multifocal leukoencephalopathy. Anti-JC virus (Anti-JCV) antibody prevalence in a large, geographically diverse, multi-nationalExpand
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