Biological and medical significance of calcium phosphates.
- S. Dorozhkin, M. Epple
- Materials Science, MedicineAngewandte Chemie
- 2 September 2002
Calcium phosphates have a great biological and medical significance and in this review, an overview of the current knowledge in this subject is given.
TOXICITY OF SILVER NANOPARTICLES INCREASES DURING STORAGE BECAUSE OF SLOW DISSOLUTION UNDER RELEASE OF SILVER IONS
- S. Kittler, C. Greulich, J. Diendorf, M. Köller, M. Epple
- Materials Science
- 30 July 2010
The dissolution of citrate-stabilized and poly(vinylpyrrolidone)-stabilized silver nanoparticles in water was studied by dialysis for up to 125 days at 5, 25, and 37 °C. The particles slowly dissolve…
Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy.
- V. Sokolova, Anna-Kristin Ludwig, B. Giebel
- BiologyColloids and Surfaces B: Biointerfaces
- 1 October 2011
MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease
- L. Kordelas, V. Rebmann, B. Giebel
- Materials ScienceLeukemia
- 1 April 2014
The molecular analysis designed the molecular analysis and funded it, analyzed GEP data and wrote the manuscript, and the statistical analysis was performed by PPP and MR.
Studies on the biocompatibility and the interaction of silver nanoparticles with human mesenchymal stem cells (hMSCs)
- C. Greulich, S. Kittler, M. Epple, G. Muhr, M. Köller
- Biology, Materials ScienceLangenbeck's archives of surgery (Print)
- 12 March 2009
It is shown that Ag-NPs exert cytotoxic effects on hMSCs at high concentrations but also induce cell activation at high but nontoxic concentrations of nanosilver.
Silver as Antibacterial Agent: Ion, Nanoparticle, and Metal
- S. Chernousova, M. Epple
- Chemistry
- 11 June 2013
Silver as antibacterial agent: ion, nanoparticle, and metal.
- S. Chernousova, M. Epple
- EngineeringAngewandte Chemie
- 4 February 2013
It can be concluded that the therapeutic window for silver is narrower than often assumed, however, the risks for humans and the environment are probably limited.
Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells: A Potential Mechanism in Atherosclerotic Plaque Destabilization
- Alexandra E. Ewence, M. Bootman, D. Proudfoot
- BiologyCirculation Research
- 29 August 2008
It is found that small calcium phosphate crystals could destabilize atherosclerotic plaques by initiating inflammation and by causing vascular smooth muscle cell death in human aortic vascular smooth Muscle cells with their potency depending on their size and composition.
The toxic effect of silver ions and silver nanoparticles towards bacteria and human cells occurs in the same concentration range
- C. Greulich, D. Braun, M. Köller
- Biology
- 23 July 2012
Comparative studies with both silver ions and silver nanoparticles showed that the toxic effect of silver occurs in a similar concentration range for Escherichia coli, Staphylococcus aureus, human mesenchymal stem cells (hMSCs), and peripheral blood mononuclear cells (PBMCs).
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