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Darapladib for preventing ischemic events in stable coronary heart disease.
BACKGROUND Elevated lipoprotein-associated phospholipase A2 activity promotes the development of vulnerable atherosclerotic plaques, and elevated plasma levels of this enzyme are associated with an… Expand
"European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses.
- D. Mikhailidis, M. Elisaf, +15 authors E. Liberopoulos
- Current vascular pharmacology
- 31 August 2011
Aim of the present Consensus Statement is to provide a comprehensive and up to-date document on the pathophysiology, atherogenicity and clinical significance of low density liproproteins (LDL)… Expand
Centralized Pan-European survey on the under-treatment of hypercholesterolaemia (CEPHEUS): overall findings from eight countries
- M. Hermans, M. Castro Cabezas, +5 authors V. Sansoy
- Current medical research and opinion
- 15 January 2010
Abstract Background: Surveys evaluating plasma lipid goal attainment in patients with coronary heart disease have shown that hypercholesterolaemia is inadequately treated. Limited data account for… Expand
Atherogenic lipid and lipoprotein parameters in hemodialysis patients
The treatment of coronary heart disease: an update. Part 1: An overview of the risk factors for cardiovascular disease.
- M. Elisaf
Cardiovascular disease (CVD) is the main cause of death. Atherosclerosis of coronary arteries is responsible for almost all cases of CVD. The term 'risk factor' describes all those characteristics… Expand
Metabolic Syndrome: Clinical Features Leading to Therapeutic Strategies
Lipid testing in infectious diseases: possible role in diagnosis and prognosis
IntroductionAcute infections lead to significant alterations in metabolic regulation including lipids and lipoproteins, which play a central role in the host immune response. In this regard, several… Expand
Effect of Fenofibrate on Serum Inflammatory Markers in Patients With High Triglyceride Values
Background: Atherosclerosis is the leading cause of death in developed countries. Although the mechanisms that underlie this process are not well defined, it has been proposed that atherosclerosis is… Expand
The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia
ABSTRACT Background: Increased concentrations of low density lipoprotein cholesterol (LDL-C), as well as of small dense LDL-C (sdLDL-C), are considered as cardiovascular risk factors. Objective: An… Expand
Effect of HMG-CoA reductase inhibitors on vascular cell apoptosis: beneficial or detrimental?
- N. Katsiki, K. Tziomalos, Y. Chatzizisis, M. Elisaf, A. Hatzitolios
- 1 July 2010
Vascular cell apoptosis, an active form of programmed cell death, plays an integral role in atherosclerosis and in-stent restenosis after angioplasty, thus promoting the precipitation of acute… Expand