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A randomized, controlled trial of surgery for temporal-lobe epilepsy.
- S. Wiebe, W. Blume, J. Girvin, M. Eliasziw
- Medicine, PsychologyThe New England journal of medicine
- 2 August 2001
In temporal-lobe epilepsy, surgery is superior to prolonged medical therapy, and Randomized trials of surgery for epilepsy are feasible and appear to yield precise estimates of treatment effects.
Sample size and optimal designs for reliability studies.
A functional approximation to earlier exact results is shown to have excellent agreement with the exact results and one can use it easily without intensive numerical computation.
Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators.
Benefit of carotid endarterectomy was greatest among men, patients with recent stroke as the qualifying event, and patients with hemispheric symptoms, and decisions about treatment for patients in this category must take into account recognized risk factors.
Sample size requirements for reliability studies.
This paper provides exact power contours to guide the planning of reliability studies, where the parameter of interest is the coefficient of intraclass correlation rho derived from a one-way analysis…
Carotid artery stenosis: gray-scale and Doppler US diagnosis--Society of Radiologists in Ultrasound Consensus Conference.
A multidisciplinary panel of experts in the field of vascular ultrasonography (US) to come to a consensus regarding Doppler US for assistance in the diagnosis of carotid artery stenosis identified several important unanswered questions meriting future research.
The North American Symptomatic Carotid Endarterectomy Trial : surgical results in 1415 patients.
The overall rate of perioperative stroke and death was 6.5%, but the rate of permanently disabling stroke anddeath was only 2.0%, indicating that carotid endarterectomy is a durable procedure.
Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.
Carotid endarterectomy is highly beneficial to patients with recent hemispheric and retinal transient ischemic attacks or nondisabling strokes and ipsilateral high-grade stenosis of the internal carotid artery.
Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery
Statistical methodology for the concurrent assessment of interrater and intrarater reliability: using goniometric measurements as an example.
It is recommended that when both interrater and intrarater reliability are being assessed, a repeated-measures design be used to take advantage of the increased precision gained by using all observations in the statistical analysis, and appropriate statistical tests, confidence intervals, and SEMs always be used in conjunction with the estimated reliability coefficients.
Relationship between middle cerebral artery blood velocity and end-tidal PCO2 in the hypocapnic-hypercapnic range in humans.
The relationship between cerebral blood flow (CBF) and end-tidal PCO2 (PETCO2) in humans is examined to determine middle cerebral artery peak blood velocity responses to PETCO2 and there was evidence of hysteresis in the CBF-PetCO2 sensitivity.