• Publications
  • Influence
Zebrafish hox clusters and vertebrate genome evolution.
Teleosts, the most species-rich group of vertebrates, appear to have more copies of these developmental regulatory genes than do mammals, despite less complexity in the anterior-posterior axis.
Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes.
A model whereby swirl/bmp2b acts as a morphogen to specify different cell types along the dorsoventral axis is proposed, suggesting that the previously described nonneural/neural ectodermal interaction specifying the neural crest occurs through a patterning function of swirl/BMP2b during gastrulation.
Combinatorial expression of three zebrafish genes related to distal- less: part of a homeobox gene code for the head
It is suggested that combinatorial expression of the dlx genes is part of a homeobox gene code specifying pattern formation or cell fate determination in the forebrain, in peripheral structures of the head, and in the fins.
A Subpopulation of Olfactory Bulb GABAergic Interneurons Is Derived from Emx1- and Dlx5/6-Expressing Progenitors
The results suggest that some OB interneurons are derived from progenitors outside the LGE and that precursors expressing what has classically been considered a pallial transcription factor generate GABAergic interneeurons.
The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus
The direct endocannabinoid-mediated control of hippocampal glutamatergic neurotransmission may constitute a promising therapeutic target for the treatment of disorders associated with excessive excitatory neuronal activity.
A Highly Conserved Enhancer in the Dlx5/Dlx6Intergenic Region is the Site of Cross-Regulatory Interactions betweenDlx Genes in the Embryonic Forebrain
It is proposed that the Dlx genes are part of a highly conserved developmental pathway that regulates forebrain development and is supported by cotransfection and DNA-protein binding experiments.
Involvement of the sonic hedgehog, patched 1 and bmp2 genes in patterning of the zebrafish dermal fin rays.
A role for shh, ptc1 and bmp2 in patterning of the dermoskeleton of developing and regenerating teleost fins is suggested.
Radiation hybrid mapping of the zebrafish genome.
Mapping expressed sequence tags and cloned genes by using the LN54 panel should prove to be a valuable method for the identification of candidate genes for specific mutations in zebrafish.
Differential induction of four msx homeobox genes during fin development and regeneration in zebrafish.
Analysis of the expression of four homeobox genes in zebrafish fins suggests distinct roles for each of the four msx genes during fin development and regeneration and differential regulation of their expression.
Nitrogen excretion in developing zebrafish (Danio rerio): a role for Rh proteins and urea transporters.
Injection of antisense oligonucleotide morpholinos to elicit selective gene knockdown of ammonia (Rhag, Rhbg, and Rhcg1) or urea transporters (UT) was used as a tool to assess the relative importance