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Prenatal maternal restraint stress exposure alters the reproductive hormone profile and testis development of the rat male offspring
Abstract Several studies have demonstrated that the presence of stressors during pregnancy induces adverse effects on the neuroendocrine system of the offspring later in life. In the present work, weExpand
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Gestational Restraint Stress and the Developing Dopaminergic System: An Overview
Prenatal stress exerts a strong impact on fetal brain development in rats impairing adaptation to stressful conditions, subsequent vulnerability to anxiety, altered sexual function, and enhancedExpand
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Effects of prenatal stress on motor performance and anxiety behavior in Swiss mice
Stressor presence during the last weeks of gestation has been associated with behavioral disorders in later life. In this study we support further research on the long term effects of prenatal stressExpand
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Age-Dependent Effects of Prenatal Stress on the Corticolimbic Dopaminergic System Development in the Rat Male Offspring
We have previously demonstrated that prenatal stress (PS) exerts an impairment of midbrain dopaminergic (DA) system metabolism especially after puberty, suggesting a particular sensitivity of DAExpand
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Long-term consequences of prenatal stress and neurotoxicants exposure on neurodevelopment
HIGHLIGHTSExposure to insults in‐utero may have negative effects on the development of target organs, increasing the risk of adult diseases.Current understanding presumes that the interaction ofExpand
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Maternal administration of flutamide during late gestation affects the brain and reproductive organs development in the rat male offspring
We have previously demonstrated that male rats exposed to stress during the last week of gestation present age-specific impairments of brain development. Since the organization of the fetalExpand
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Prenatal stress changes the glycoprotein GPM6A gene expression and induces epigenetic changes in rat offspring brain
Prenatal stress (PS) exerts strong impact on fetal brain development and on adult offspring brain functions. Previous work demonstrated that chronic stress alters the mRNA expression of GPM6A, aExpand
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Prenatal restraint stress decreases the expression of alpha-7 nicotinic receptor in the brain of adult rat offspring
Abstract Prenatal stress (PS) strongly impacts fetal brain development and function in adulthood. In normal aging and Alzheimer's disease, there is hypothalamic–pituitary–adrenal axis dysfunction andExpand
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Glutamate neurotransmission is affected in prenatally stressed offspring
Previous studies from our laboratory have shown that male adult offspring of stressed mothers exhibited higher levels of ionotropic and metabotropic glutamate receptors than control rats. TheseExpand
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Prenatal Stress and Neurodevelopmental Plasticity: Relevance to Psychopathology.
Prenatal development constitutes a critical time for shaping adult behaviour and may set the stage for vulnerability to disease later in life. A wealth of information from humans as well as fromExpand
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