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Nitric oxide assay using hemoglobin method.
Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP‐sensitive potassium channels.
1. Nitric oxide (NO) relaxes vascular smooth muscle (VSM) by mechanisms which are not fully understood. One possibility is that NO hyperpolarizes membranes, thereby diminishing Ca2+ entry throughExpand
Apamin‐sensitive K+ channels mediate an endothelium‐dependent hyperpolarization in rabbit mesenteric arteries.
1. Vascular endothelial cells release a variety of substances which affect the membrane potential and tone of underlying vascular smooth muscle. In the presence of N omega‐nitro‐L‐arginine to inhibitExpand
In vitro antiviral activity of lactoferrin and ribavirin upon hantavirus
Summary. Bovine lactoferrin (LF) and ribavirin (Rbv) were tested as antiviral agents against Seoul type hantavirus (SR-11 strain) in vitro. Hantaviral foci number in Vero E6 cells infected with SR-11Expand
Naphthalene cytotoxicity of differentiating Clara cells in neonatal mice.
Selective Clara cell injury produced by many bioactivated lung toxicants is thought to result from high levels of activating enzymes found in differentiated Clara cells. A recent study found anExpand
Pulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice.
Various studies indicate that cytodifferentiation of Clara cells and development of pulmonary cytochrome P450 (CYP) monooxygenases occur postnatally. The timing of these events is species-specific.Expand
Development of phase II xenobiotic metabolizing enzymes in differentiating murine clara cells.
Glutathione S-transferases (GSTs) and epoxide hydrolases (EHs) protect cells from exogenous insult by detoxifying electrophilic compounds. Little is known about these enzyme systems during postnatalExpand
The Effects of Amine-Carboxyborane Related Derivatives on UMR-106 Bone Metabolism
The amine-carboxyboranes and related derivatives have been shown to be potent anti-inflammatory and anti-osteoporosis agents. Their action in part appears to be mediated by the modulation ofExpand
Anti-Inflammatory Activity of (Polyphenolic)-Sulfonates and Their Sodium Salts in Rodents
A series of polyphenolic-sulfonated compounds were observed to have potent anti-inflammatory activity and were protective against induced endotoxic shock in mice at 8 and 16 mg/kg, I.P. These agentsExpand