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Excitatory amino acid receptor antagonist kynurenic acid attenuates rewarding potential of morphine.
The effect of the non-selective antagonist of excitatory amino acid receptors kynurenic acid (50, 100 and 150 mg/kg, i.p.) on morphine-derived reward was studied in rats. Kynurenic acid doseExpand
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Fullerene C60 Complexed with Poly(N-Vinyl-pyrrolidone) (C60/PVP) Prevents the Disturbance of Long-Term Memory Consolidation Induced by Cycloheximide
Abstract It is shown that fullerene C60/water‐soluble complex with PVP molecular mass of 10,000 injected in the dorsal hippocampus completely prevents the development of amnesia caused byExpand
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Fullerene C60 complexed with poly(N-vinyl-pyrrolidone) prevents the disturbance of long-term memory consolidation
A microinjection of C60/poly-(N-vinyl-pyrrolidone) (C60/PVP) adduct into the dorsal hippocampus is shown to prevent the disturbance of spatial memory consolidation induced by the administration of aExpand
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[Antiviral activity of fullerene (60)C complexed with poly(N-vinylpyrrolidone)].
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Excitatory action of some aspartate- and glutamate-containing dipeptides after intracerebroventricular injection in mice.
The effects of some dipeptides, analogues of N-acetyl-alpha-L-aspartyl-L-glutamate, were studied after i.c.v. administration into mice in acute experiments. N-Acetyl-alpha-L-aspartyl-L-glutamateExpand
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Enhanced brain penetration of hexamethonium in complexes with derivatives of fullerene C60
The present report describes development of hexamethonium complexes based on fullerene C60. Hexamethonium has a limited penetration into CNS and therefore can antagonize central effects of nicotineExpand
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Pristine Fullerene C60: Different Water Soluble Forms—Different Mechanisms of Biological Action
Abstract Aqueous fullerene preparations, namely complex of C60 with polyvinylpyrrolidone (C60/PVP) and molecular‐colloidal water solutions of C60 (FWS) exhibit virocidal activity due to differentExpand
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A novel selective NMDA agonist, N-phthalamoyl-L-glutamic acid (PhGA).
Ionic currents elicited by N-phthalamoyl-L-glutamic acid (PhGA) were investigated on freshly isolated hippocampal neurons with the whole-cell voltage clamp and concentration clamp techniques. PhGAExpand
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Selective alkylation of imidazole-4(5)-carboxamides
Alkylation of imidazole-4(b)-carboxamides by alkyl halides or dimethylsulfate leads to the selective formation of 1-alkyl-imidazole-4-carboxamides.
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Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid.
Three amino-alkylated derivatives of the naturally occurring excitatory amino acid (EAA) receptor agonist ibotenic acid (Ibo) have been synthesized and tested pharmacologically. N-Methyl-Ibo (1a) andExpand
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