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The nitric oxide-scavenging properties of Ginkgo biloba extract EGb 761.
TLDR
Data implicate Ginkgo biloba extract EGb 761 as a potential therapeutic agent in conditions of altered production of nitric oxide in in vitro acellular systems. Expand
A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress.
TLDR
Treatment with the Ginkgo biloba extract EGb 761 partially prevented these morphological changes as well as the indices of oxidative damage observed in brain and liver mitochondria from old animals. Expand
Ischemia and reperfusion-induced histologic changes in the rat retina. Demonstration of a free radical-mediated mechanism.
TLDR
The SOD and EGB 761 significantly reduced the development of reperfusion-induced retinal edema and significantly prevented the neutrophil leukocyte infiltration and had a protective effect against reperfusions-induced injury when these agents were administered just before reperfuse ("late" administration). Expand
Antioxidant action of Ginkgo biloba extract EGb 761.
TLDR
EGb 761 is a dry, powdered extract prepared from Ginkgo biloba leaves that is a standardized mixture of several different chemical constituents; its two major classes of compounds are flavonoid glycosides and terpenoids. Expand
Peroxyl radical scavenging activity of Ginkgo biloba extract EGb 761.
TLDR
EGb 761 afforded protection against oxidative damage in all the systems the authors analyzed and is an efficient scavenger of peroxyl radicals, which supports the hypothesis of an antioxidant therapeutic action of EGb 7 61. Expand
Ginkgo biloba extract (EGb 761): inhibitory effect on nitric oxide production in the macrophage cell line RAW 264.7.
TLDR
Findings indicate that not only does EGb 761 directly act as an NO scavenger but also that it inhibits NO production in LPS/IFN-gamma-activated macrophages by concomitant inhibition of induction ofiNOS mRNA and the enzyme activity of iNOS. Expand
The protective effect of EGb 761 in isolated ischemic/reperfused rat hearts: a link between cardiac function and nitric oxide production.
TLDR
The findings show that EGb 761 directly acts as an NO scavenger and concomitantly inhibits the expression of iNOS mRNA, and may act as a potent inhibitor of NO production under the condition of ischemia/reperfusion, improving the recovery of postischemic cardiac function. Expand
EGb 761 protects liver mitochondria against injury induced by in vitro anoxia/reoxygenation.
TLDR
EGb 761 specially protects mitochondrial ATP synthesis against anoxia/reoxygenation injury by scavenging the superoxide anion generated by mitochondria. Expand
Effects of natural antioxidant ginkgo biloba extract (EGB 761) on myocardial ischemia-reperfusion injury.
TLDR
Results indicate that EGb 761 protects against cardiac ischemia-reperfusion injury and suggest that the protective effects of EGB 761 depend on its antioxidant properties. Expand
Functional protection of photoreceptors from light-induced damage by dimethylthiourea and Ginkgo biloba extract.
TLDR
Dimethylthiourea and EGb 761 afford functional protection against light-induced retinal damage, and the outer nuclear layer thicknesses decreased markedly in the superior retina. Expand
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