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Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach.
TLDR
The "normal" central corneal thickness (CCT) value in human corneas was determined based on reported literature values for within-study average CCT values, and the reported impact of physiological variables, contact lens wear, pharmaceuticals, ocular disease, and ophthalmic surgery on CCT was assessed.
Consideration of Three Types of Spontaneous Eyeblink Activity in Normal Humans: during Reading and Video Display Terminal Use, in Primary Gaze, and while in Conversation
  • M. Doughty
  • Psychology, Medicine
    Optometry and vision science : official…
  • 1 October 2001
TLDR
The conditions under which the so-called spontaneous (endogenous) eyeblink activity has been assessed by different investigators over the last 75 years are considered and it is proposed that reports of SEBR measures should be prefixed by these experimental conditions, namely reading-SEBR, primary gaze- SEBR (in silence) and conversational-SE BR.
A Patient Questionnaire Approach to Estimating the Prevalence of Dry Eye Symptoms in Patients Presenting to Optometric Practices across Canada
TLDR
The prevalence of patients reporting any level of symptoms of dry eyes was approximately 1 in 4; severe symptoms were reported by 1 in 225 patients.
The tear (lacrimal) meniscus height in human eyes: a useful clinical measure or an unusable variable sign?
TLDR
The average TMH value of close to 0.2mm in the elderly, as compared to the small number of individuals with rather greater TMH values, might therefore be considered as indicative of their having normal tear volume, with a few individuals having reflex tearing.
The exposed ocular surface and its relationship to spontaneous eyeblink rate in elderly caucasians.
TLDR
The exposed ocular surface area per se does not appear to be an important determinant of spontaneous eyeblink activity in elderly Caucasians.
Efficacy of different dry eye treatments with artificial tears or ocular lubricants: a systematic review
Purpose:  To objectively review the outcome of clinical studies where rose bengal stain (RB) has been used as an outcome measure to assess the efficacy of artificial tears (AT) in patients with dry
Further Assessment of Gender- and Blink Pattern-Related Differences in the Spontaneous Eyeblink Activity in Primary Gaze in Young Adult Humans
  • M. Doughty
  • Psychology, Medicine
    Optometry and vision science : official…
  • 1 July 2002
TLDR
It is proposed that the pattern of spontaneous eyeblink activity where there are similar intervals between each eyeblink event should be referred to as a “normal” (rather than symmetrical) pattern and should be considered as the normal eyeblinks activity, both from a physiological and statistical perspective.
A Comparison of Tear Volume (by Tear Meniscus Height and Phenol Red Thread Test) and Tear Fluid Osmolality Measures in Non-Lens Wearers and in Contact Lens Wearers
TLDR
The changes are internally consistent and support the idea that the PRT test provides a useful measure of tear meniscus volume, and even contemporary contact lens wear can have a small but measurable impact on the precorneal tear film osmolality or volume.
The Orbscan Acoustic (Correction) Factor for Central Corneal Thickness Measures of Normal Human Corneas
TLDR
The global application of a 0.92 AF does not robustly align the Orbscan CCT data to that of U/S and, in fact, can easily result in the data being as much as 7% lower.
pH dependent spectral properties of sodium fluorescein ophthalmic solutions revisited
  • M. Doughty
  • Chemistry, Medicine
    Ophthalmic & physiological optics : the journal…
  • 1 March 2010
Purpose:  To re‐assess and further quantify the pH‐related changes in the absorbance and fluorescence emission spectra of sodium fluorescein in buffered aqueous solutions.
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