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Design, evaluation and structure—Activity relationship studies of the AChE reactivators against organophosphorus pesticides
TLDR
This review is the summarized design, evaluation, and structure–activity relationship studies of recently produced AChE reactivators against OPP, and several novel compounds show very promising abilities as comparable to commercial oximes.
Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase.
TLDR
Six AChE monooxime-monocarbamoyl reactivators with an (E)-but-2-ene linker were synthesized using modification of currently known synthetic pathways and according to the results obtained, one reactivator seems to be promising against tabun-inhibited A ChE and two reactvators against paraoxon-in inhibited ACh E.
Synthesis and Disinfection Effect of the Pyridine-4-aldoxime Based Salts
A set of new quaternary ammonium compounds based on pyridine-4-aldoxime was synthesized, characterized with analytical data (NMR, EA, HPLC, MS) and tested for in vitro antimicrobial activity
Pyrazine derivatives: a patent review (June 2012 – present)
TLDR
This review is a survey of important patents on pyrazine derivatives with pharmacological activity published in the period June 2012 – July 2014 and expects that several of these compounds will add to existing pharmaceuticals in the very near future.
Neurocysticercosis and oncogenesis.
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