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- Publications
- Influence
Coenzyme Q10 oral bioavailability: effect of formulation type
- A. Barakat, R. Shegokar, M. Dittgen, R. Müller
- Chemistry
- Journal of Pharmaceutical Investigation
- 4 October 2013
Abstract
Coenzyme Q10 (Q10) has a poor bioavailability due to its very low aqueous solubility and high molecular weight. The purpose of this review is to discuss the different types of Q10 drug… Expand
Adhesive Backing Foil Interactions Affecting the Elasticity, Adhesion Strength of Laminates, and How to Interpret These Properties of Branded Transdermal Patches
- C. Fauth, S. Wiedersberg, R. H. Neubert, M. Dittgen
- Materials Science, Medicine
- Drug development and industrial pharmacy
- 1 January 2002
ABSTRACT Standard tensile strength and peel adhesion tests were carried out to investigate interactions of pressure-sensitive adhesives (PSAs) with several backing foils used for transdermal patches.… Expand
Evaluation of an oral pulsatile delivery system for melatonin in humans.
- H. Hoffmann, M. Dittgen, +9 authors M. Oettel
- Medicine
- Die Pharmazie
- 1 July 1998
Using melatonin (MT) as a circadian synchroniser in humans to treat a variety of rhythm disorders, it is desirable to develop controlled-release dosage forms that deliver MT in accordance with its… Expand
Acrylic acid copolymer nanoparticles for drug delivery: structural characterization of nanoparticles by small-angle x-ray scattering
- J. J. Mueller, G. Lukowski, R. Kröber, G. Damaschun, M. Dittgen
- Chemistry
- 1 July 1994
Nanoparticles are possible carriers for drug delivery. Copolymer nanoparticles of acrylic acid, acrylic amide, acrylic butylester, and methacrylic methylester (CAA) dispersed in water and in 0.15 M… Expand
[Pharmaceutical granulation technology].
- M. Dittgen, H. Kala, H. Moldenhauer, G. Zessin, J. Schneider
- Chemistry, Medicine
- Die Pharmazie
- 1980
Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid.
- M. Rajab, M. Jouma, R. Neubert, M. Dittgen
- Materials Science, Medicine
- Die Pharmazie
- 1 February 2010
This study optimizes the composition of an effervescent floating tablet (EFT) containing metformin hydrochloride (M) regarding tablet hardness (H), time to dissolve 60% of the embedded drug (t60%),… Expand
Hot spin mixing : a new technology to manufacture solid dispersions. III: Progesterone
- M. Dittgen, S. Fricke, H. Gerecke, Hermann Dr Osterwald
- Chemistry
- 1995
- 19
Relationship Between film Properties and Drug Release from Acrylic Films
- M. Dittgen
- Materials Science
- 1985
AbstractAn in vitro technique was used to determine the release rates of drugs from different acrylic copolymers as carrier systems. The drugs used in this investigation were pilocarpine,… Expand
[The storage capability of pre-filled disposable plastic syringes].
- G. Doege, M. Dittgen, S. Garbe
- Chemistry, Medicine
- Die Pharmazie
- 1 August 1985
The storage stability of a pre-filled plastic disposable syringe (piston type) of polypropylene as to solvents and ambient oxygen has been studied. To assess the permeability and impermeability of… Expand
X-ray diffraction, differential scanning calorimetry and thermogravimetry combined with infrared analysis of freeze-dried prednisolone hemisuccinate.
- S. Claussen, M. Boese, M. Dittgen
- Medicine, Chemistry
- Die Pharmazie
- 1 June 2001
In this study, the thermal behaviour of freeze-dried prednisolone hemisuccinate (Prednisolut) was investigated by means of X-ray scattering, differential scanning calorimetry (DSC) and fourier… Expand