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Neonatal management. Role for early intervention.
It is demonstrated that prolonged partial UPJ obstruction in the developing kidney causes significant renal morbidity with time and early intervention is the more "conservative" or safe method of treatment for infants with ureteropelvic junction obstruction. Expand
The effect of testosterone on androgen receptors and human penile growth.
The hypothesis that penile growth cessation is mediated by mechanisms other than down regulation of the androgen receptor is supported, and these data support the hypothesis that early administration of androgen to prepubertal male individuals does not result in a shorter phallus in adulthood. Expand
Growth factors in bladder wound healing.
During the early phases of bladder wound healing, mRNA for KGF and TGF alpha increased, whereas TGF beta 2 and beta 3 and the KGFR and EGFR remain unchanged, whereas exogenous KGF has a direct effect on urothelial proliferation. Expand
Mesenchymal-epithelial interactions in bladder smooth muscle development: epithelial specificity.
Bladder epithelium induced intestinal, gastric and seminal vesicle mesenchyme to differentiate into smooth muscle and express an overall morphological pattern indicative of the bladder fibromuscular wall, which was independent of urothelial age. Expand
Outcomes of continent catheterizable stomas for urinary and fecal incontinence: comparison among different tissue options
To retrospectively review the outcome of appendix, transverse tubularized intestine segments, caecal flap, gastric tube and others tissue options used as a continent stoma for urinary and fecalExpand
Bladder neck sling for treatment of neurogenic incontinence in children with augmentation cystoplasty: long-term followup.
B bladder neck slings are considered the procedure of choice for the enhancement of bladder outlet resistance in the majority of patients with neurogenic bladder who need augmentation cystoplasty and whom the authors do not expect will be capable of voiding spontaneously. Expand
Mesenchymal-epithelial interactions in the bladder
SummaryDuring bladder development, undifferentiated mesenchymal and epithelial cells undergo an orderly sequence of differentiation defined by the expression of smooth-muscle (α-actin, myosin,Expand
Gender identity in disorders of sex development: review article.
A literature review which addresses the challenges of advising families about gender identity in infants and children with disorders of sex development and the evidence for endocrine effects on neurobiological development with regard to sexual behavior is compelling. Expand
Do adult men with untreated hypospadias have adverse outcomes? A pilot study using a social media advertised survey.
It is hypothesized that men with untreated hypospadias, especially mild, do not have adverse outcomes, and research is needed to determine if treatment of childhood hypos padias improves outcomes in adults. Expand
Stricture incidence related to suture material in hypospadias surgery.
Sutures with rapid or intermediate absorption rates provide the best results for hypospadias surgery, and the extreme delay in in vivo absorption of polydioxanone should preclude its use as an interrupted suture in small-caliber urethral anastomoses. Expand