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  • Edward H. Lin, Steven A. Curley, +10 authors Nora A. Janjan
  • Medicine
  • American journal of clinical oncology
  • 2006 (First Published: 1 June 2006)
  • OBJECTIVE COX-2 activation may mediate capecitabine induced toxicities, eg, hand-foot syndrome (HFS) and colorectal cancer progression, both of which may be improved by concurrent celecoxib. Continue Reading
  • Edward H. Lin, Gretchen Ayer, +7 authors Steven A. Curley
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2004 (First Published: 15 July 2004)
  • 3584 Background: Cyclooxygenase-2 (COX-2) is a putative therapeutic target for MCRC and may also be the culprit of X-induced HFS. Treatment (tx) of MCRC with X + CEL, a specific COX-2 inhibitor,Continue Reading