M. Deinzer

Publications177
h-index39
Citations5,915
Highly Influential Citations183
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Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry.
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Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.
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Pyrrolizidine alkaloids: their occurrence in honey from tansy ragwort (Senecio jacobaea L.)
TLDR
The hepatotoxic alkaloids known to occur in tansy ragwort (Senecio jacobaea L.) are also present in honey produced from the nectar of this species and may pose health hazards to the human consumer.
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Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro.
TLDR
It is suggested that prenylchalcones and prenylflavanones found in hops and beer protect human LDL from oxidation and thatPrenylation antagonizes the prooxidant effects of the chalcone, CN, and the flavanone, NG.
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In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus
TLDR
It is suggested that the hop flavonoids are potent and selective inhibitors of human cytochrome P450 and warrant further in vivo investigations.
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Fate of xanthohumol and related prenylflavonoids from hops to beer.
TLDR
Solubility experiments indicated that (1) malt carbohydrates form soluble complexes with xanthohumol and isoxanthohumsol and (2) solubility does not dictate the isxanthohUMol levels of finished beers.
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Hop (Humulus lupulus L.) proanthocyanidins characterized by mass spectrometry, acid catalysis, and gel permeation chromatography.
TLDR
In the last-eluted fraction, polymers as large as 20-mers were detected by MALDI-TOF-MS, demonstrating the effectiveness of prior separation in improving MS detection and GPC data correlated well with acid catalysis results, confirming the presence of large polymers that were not detected by MS.
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Tandem mass spectrometry for sequencing proanthocyanidins.
TLDR
It is shown that the protocol based on a combination of these different fragmentation patterns allows for uniquely identifying PA oligomers.
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The endocrine activities of 8-prenylnaringenin and related hop (Humulus lupulus L.) flavonoids.
TLDR
The results indicate that the endocrine properties of hops and hop products are due to the very high estrogenic activity of 8-prenylnaringenin and concern must be expressed about the unrestricted use of hops in herbal preparations for women.
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Prenylflavonoid variation in Humulus lupulus: distribution and taxonomic significance of xanthogalenol and 4'-O-methylxanthohumol.
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