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Novel steroid inhibitors of glucose 6-phosphate dehydrogenase.
TLDR
Novel derivatives of the steroid DHEA 1, a known uncompetitive inhibitor of G6PD, were designed, synthesized, and tested for their ability to inhibit this dehydrogenase enzyme and generally have good physicochemical properties and satisfactory in vitro DMPK parameters. Expand
CARBAMYLATION AND DECARBAMYLATION OF ACETYLCHOLINESTERASE: EFFECT OF CHOLINE, 3,3‐DIMETHYL‐l‐BUTANOL AND SOME ALLOSTERIC EFFECTORS
  • M. Dawson
  • Chemistry, Medicine
  • Journal of neurochemistry
  • 1 April 1978
TLDR
The results provide further support for a previous proposal that choline and DMB bind to different sites on the enzyme, despite their structural similarity. Expand
Asymmetric hydrogenation of 2-methylpyridine to 2-methylpiperidine. raney-nickel modified with a molecular template
Raney-nickel catalysts templated as per Izumi, 1) have been used for the asymmetric hydrogenation of 2-methylpyridine to (d)-2-methylpiperidine. This represents the first example of asymmetricExpand
Biopterin. VI. Purification and primary amino acid sequence of mammalian D-erythro-7,8-dihydroneopterin triphosphate synthetase.
TLDR
An enzyme that catalyzes the conversion of 2-amino-5- or 6-formamido-6-hydroxypyrimidine to quinonoid 6-(D-erythro-1'-2'-3'-trihydroxypropyl)dihydropterin triphosphate and formic acid has been purified to homogeneity from some mammalian brain and liver. Expand