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Guidelines on the management of Paget's disease of bone.
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Parafibromin mutations in hereditary hyperparathyroidism syndromes and parathyroid tumours
TLDR
This data indicates that the HPT‐JT syndrome and FIHP are autosomal dominant disorders that may be caused by abnormalities of the HRPT2 gene, which encodes a 531 amino acid protein, parafibromin, which interacts with human homologues of the yeast Paf1 complex.
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Effects of dissociated glucocorticoids on OPG and RANKL in osteoblastic cells.
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Paget's disease of bone: a review of 889 patients.
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Knee Angles and Rickets in Nigerian Children
TLDR
Knee angles of 2,036 normal Nigerian children up to 12 years old were measured directly or from photographs, finding that varus knee is uncommon after 2 years, and large knee angles between 2 and 5 years suggest rickets.
View on Wolters Kluwer
Relative contributions of diet and sunlight to vitamin D state in the elderly.
TLDR
To maintain plasma concentrations in the elderly above those associated with osteomalacia a mean dietary vitamin D intake of over 5 microgram/day is required, however, a more physiological approach would be to increase exposure to UVL.
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Sarcoma arising in Paget's disease of bone: declining incidence and increasing age at presentation.
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Risedronate Reduces the Risk of First Vertebral Fracture in Osteoporotic Women
TLDR
Risedronate treatment significantly reduces the risk of first vertebral fracture in postmenopausal women with osteoporosis, with a similar magnitude of effect early and late after the menopause.
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Excess non-spine fractures in women over 50 years with celiac disease: A cross-sectional, questionnaire-based study
TLDR
Fracture risk in female celiac patients >50 years is increased overall but is related largely to the peri-diagnostic period, and celiac testing may be indicated in thin women over 50 years with multiple fractures, and after diagnosis adequate calcium and vitamin D intake should be ensured.
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1-Alpha-hydroxycholecalciferol as a substitute for the kidney hormone 1,25-dihydroxycholecalciferol in chronic renal failure.
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