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Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis.
The results provide compelling evidence for the preferential utilization of either signaling component by particular R genes and thus define at least two disease resistance pathways and suggest that strong dependence on EDS1 or NDR1 is governed by R protein structural type rather than pathogen class. Expand
Genetic diversity and introgression in the Scottish wildcat
It is argued that this is evidence that these cats do not have very recent domestic ancestry, but from the morphological data it is highly likely that this gene pool also contains a contribution from earlier introgression of domestic cat genes. Expand
A novel regulatory system required for pathogenicity of Xanthomonas campestris is mediated by a small diffusible signal molecule
A model for the DSF system is proposed, which represents a novel mechanism for regulating virulence factor synthesis in response to physiological or environmental changes and is confined to certain xanthomonads. Expand
EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases.
The results suggest that EDS1 functions upstream of salicylic acid-dependent PR1 mRNA accumulation and is not required for jasmonic acid-induced PDF1.2 mRNA expression. Expand
Pronounced Intraspecific Haplotype Divergence at the RPP5 Complex Disease Resistance Locus of Arabidopsis
It is proposed that the extremely high level of polymorphism at this complex resistance locus is maintained by frequency-dependent selection. Expand
Characterization of eds1, a mutation in Arabidopsis suppressing resistance to Peronospora parasitica specified by several different RPP genes.
An RPP-nonspecific locus called EDS1 appears to be a necessary component of the resistance response specified by several RPP genes and is likely to function upstream from the convergence of disease resistance pathways in Arabidopsis. Expand
A two‐component system involving an HD‐GYP domain protein links cell–cell signalling to pathogenicity gene expression in Xanthomonas campestris
It is proposed that RpfGHC is a signal transduction system that couples the synthesis of pathogenicity factors to sensing of environmental signals that may include DSF itself. Expand
The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the toll and interleukin-1 receptors with N and L6.
The organization of repeated units within the leucine-rich repeats encoded by the wild-type R PP5 gene and an RPP5 mutant allele provides molecular evidence for the heightened capacity of this domain to evolve novel configurations and potentially new disease resistance specificities. Expand
Cloning of genes involved in pathogenicity of Xanthomonas campestris pv. campestris using the broad host range cosmid pLAFR1
A genomic library was prepared in Escherichia coli from DNA of wild‐type Xanthomonas campestris pv. campestris (aetiological agent of crucifer black rot), partially digested with endonuclease EcoRI,Expand
Three Genes of the Arabidopsis RPP1 Complex Resistance Locus Recognize Distinct Peronospora parasitica Avirulence Determinants
Evidence is presented suggesting that the RPP genes at this locus are subject to the same selective forces that have been demonstrated for structurally different LRR-type R genes. Expand