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Tanezumab for the treatment of pain from osteoarthritis of the knee.
BACKGROUND Increased expression of nerve growth factor in injured or inflamed tissue is associated with increased pain. This proof-of-concept study was designed to investigate the safety andExpand
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Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder.
OBJECTIVE Sildenafil citrate (Viagra Pfizer, New York, NY) is indicated for the treatment of erectile dysfunction in men. The nitric oxide-cyclic guanosine monophosphate pathway (NO-cGMP) involved inExpand
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The MOBILE Study—A Phase IIa Enriched Enrollment Randomized Withdrawal Trial to Assess the Analgesic Efficacy and Safety of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Patients with
Abstract Objective To evaluate the analgesic efficacy and safety of ASP8477 in patients with peripheral neuropathic pain (PNP). Design Enriched enrollment randomized withdrawal. Setting Centers inExpand
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