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Tanezumab for the treatment of pain from osteoarthritis of the knee.
- N. Lane, T. Schnitzer, +4 authors M. Brown
- The New England journal of medicine
- 13 October 2010
BACKGROUND Increased expression of nerve growth factor in injured or inflamed tissue is associated with increased pain. This proof-of-concept study was designed to investigate the safety and… Expand
Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder.
- R. Basson, Rosemary McInnes, M. D. Smith, Gemma Hodgson, N. Koppiker
- Journal of women's health & gender-based medicine
- 1 May 2002
OBJECTIVE Sildenafil citrate (Viagra Pfizer, New York, NY) is indicated for the treatment of erectile dysfunction in men. The nitric oxide-cyclic guanosine monophosphate pathway (NO-cGMP) involved in… Expand
The MOBILE Study—A Phase IIa Enriched Enrollment Randomized Withdrawal Trial to Assess the Analgesic Efficacy and Safety of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Patients with…
Abstract Objective To evaluate the analgesic efficacy and safety of ASP8477 in patients with peripheral neuropathic pain (PNP). Design Enriched enrollment randomized withdrawal. Setting Centers in… Expand
Long Term Outcomes And Patterns Of Failure After Single Fraction Preoperative Radiosurgery For Brain Metastases