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Effect of Streptozotocin Diabetes on Selected Enzymatic Activities in Rat Urine
Summary The 24-hr urine collected from streptozotocin-diabetic rats contained activities of acid phosphatase, alkaline phosphatase, N-acetyl-β-D-glucosaminidase, α-L-fu-cosidase, β-D-galactosidase,Expand
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Prenatal withdrawal from opiates interferes with hatching of otherwise viable chick fetuses.
Fetal chicks were made opiate-dependent by injections of N-desmethyl-1-alpha-acetylmethadol into the chorioallantois on day 3 of embryogenesis. The injections had no effect on subsequentExpand
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Opiate withdrawal increases ornithine decarboxylase activity which is otherwise unaltered in brains of dependent chicken fetuses.
We have used the developing chicken to determine if ornithine decarboxylase (ODC) activity is altered in fetuses chronically exposed to the opiate N-desmethyl-l-alpha-acetylmethadol (NLAAM) orExpand
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Continuous exposure of the chick embryo to l-alpha-noracetylmethadol does not alter brain protein or nucleic acid content.
Injection of l-alpha-noracetylmethadol (NLAAM), the active des-methyl metabolite of l-alpha-acetylmethadol, into chicken eggs on the 3rd day of embryonic development produced no deficits in body orExpand
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Spin-label studies on rat liver and heart plasma membranes: Do probe-probe interactions interfere with the measurement of membrane properties?
SummaryThe structures of purified rat liver and heart plasma membranes were studied with the 5-nitroxide stearic acid spin probe,I(12, 3). ESR spectra were recorded with a 50 gauss field sweep, andExpand
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TOLERANCE AS THE ONLY SIGN OF WITHDRAWAL IN OPIATE DEPENDENT CHICK FETUSES
Tolerance is not evident in opiate-dependent chick fetuses unless they are first treated with a dose of naloxone (Nx) which doesn't block the acute depressant action of 1-α-noracetylmethadol (NLAAM)Expand