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A MicroRNA gene is hosted in an intron of a schizophrenia-susceptibility gene
The follicle cells are a major site of vitellogenin synthesis in Drosophila melanogaster.
Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase.
- D. Jones, M. D. Brennan, J. Hempel, R. Lindahl
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 1 March 1988
To study the mechanism(s) controlling expression of the tumor-associated aldehyde dehydrogenase (tumor ALDH), cDNAs encoding this isozyme were cloned and identified with an antibody probe and the larger of the cDNA clones identified, pTALDH, was chosen for further study.
Transmission disequilibrium suggests a role for the sulfotransferase‐4A1 gene in schizophrenia
- M. D. Brennan, J. Condra
- Psychology, MedicineAmerican journal of medical genetics. Part B…
- 5 November 2005
It is proposed that Sult4A merited more careful scrutiny as a candidate gene for schizophrenia susceptibility.
Regulatory gene evolution: Adaptive differences in expression of alcohol dehydrogenase in Drosophila melanogaster and Drosophila simulans
The Drosophila melanogaster × D. simulans hybrids system illustrates the potential importance of regulatory genes in evolution and provides a model for investigating the molecular basis of evolved regulatory differences.
Pharmacogenetics of second-generation antipsychotics.
- M. D. Brennan
- Biology, PsychologyPharmacogenomics
- 4 June 2014
Large-scale candidate gene studies and genome-wide association studies indicate that pharmacotypic genes may ultimately prove to be the richest source of biomarkers for response and side effect profiles for second-generation antipsychotics.
Genotypic variation in the SV2C gene impacts response to atypical antipsychotics the CATIE Study
Association of Sult4A1 SNPs with psychopathology and cognition in patients with schizophrenia or schizoaffective disorder
Polarity of transcriptional enhancement revealed by an insulator element.
A transient transformation system to evaluate the orientation preference of transcriptional enhancers in Drosophila and reveals an orientation preference for the relatively large Adh larval enhancer, used in conjunction with a luciferase reporter gene under the control of a minimal Adh promoter.
Isolation and initial characterization of the alcohol dehydrogenase gene from Drosophila affinidisjuncta.
- M. D. Brennan, R. G. Rowan, L. Rabinow, W. J. Dickinson
- BiologyJournal of molecular and applied genetics
Recombinant bacteriophages containing the alcohol dehydrogenase (ADH) gene from Drosophila affinidisjuncta have been isolated by virtue of their cross-hybridization to the previously cloned ADH gene…