• Publications
  • Influence
Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat.
The oxidation rates of lauric, myristic, palmitic, stearic, oleic, alpha-linolenic, linoleic, kappa-linolenic, dihomo-gamma-linolenic and arachidonic acids were studied by use of a radioisotopeExpand
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Brain-specific lipids from marine, lacustrine, or terrestrial food resources: potential impact on early African Homo sapiens.
The polyunsaturated fatty acid (PUFA) composition of the mammalian central nervous system is almost wholly composed of two long-chain polyunsaturated fatty acids (LC-PUFA), docosahexaenoic acid (DHA)Expand
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A double-blind, placebo-controlled study investigating the effects of omega-3 supplementation in children aged 8-10 years from a mainstream school population.
Despite the increased interest in the effects of omega-3 supplementation on children's learning and behaviour, there are a lack of controlled studies of this kind that have utilised a typicallyExpand
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Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet.
Our genome adapts slowly to changing conditions of existence. Many diseases of civilisation result from mismatches between our Paleolithic genome and the rapidly changing environment, including ourExpand
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Breast-fed infants achieve a higher rate of brain and whole body docosahexaenoate accumulation than formula-fed infants not consuming dietary docosahexaenoate
Docosahexaenoate (DHA) has been increasingly recognized as an important fatty acid for neural and visual development during the first 6 mon of life. One important point of controversy that remains isExpand
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Evidence for the unique function of docosahexaenoic acid during the evolution of the modern hominid brain
The African savanna ecosystem of the large mammals and primates was associated with a dramatic decline in relative brain capacity associated with little docosahexaenoic acid (DHA), which is requiredExpand
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Is docosahexaenoic acid (DHA) essential? Lessons from DHA status regulation, our ancient diet, epidemiology and randomized controlled trials.
The human diet has changed considerably during the last 100 y. One of the striking changes is the tremendous increase in dietary fat. In terms of quality we have increased our intakes of saturatedExpand
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Rift Valley lake fish and shellfish provided brain-specific nutrition for early Homo.
An abundant, balanced dietary intake of long-chain polyunsaturated fatty acids is an absolute requirement for sustaining the very rapid expansion of the hominid cerebral cortex during the last one toExpand
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Survival of the fattest: fat babies were the key to evolution of the large human brain.
  • S. Cunnane, M. Crawford
  • Biology, Medicine
  • Comparative biochemistry and physiology. Part A…
  • 1 September 2003
In the past 2 million years, the hominid lineage leading to modern humans evolved significantly larger and more sophisticated brains than other primates. We propose that the modern human brain was aExpand
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