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Architectural Analysis of Human Abdominal Wall Muscles: Implications for Mechanical Function
TLDR
These data provide clinically relevant insights into the ability of the abdominal wall muscles to generate force and change length throughout the lumbar spine range of motion. Expand
Age-related alterations in female obturator internus muscle
TLDR
The findings of age-related decreases in predicted OI force production and fibrosis suggest that these alterations should be taken into consideration, when designing pelvic floor fitness programs for older women. Expand
Traumatic rupture of the thoracic aorta. A review of 49 cases.
TLDR
The plain film findings found most consistently were a wide mediastinum, partial obliteration of the descending aorta, downward displacement of the left main bronchus, and tracheal deviation to the right. Expand
Structure–function relationship of the human external anal sphincter
TLDR
This first direct examination of human EAS underscores how EAS intrinsic design matches its intended function as well as investigating whether vaginal delivery alters the EAS structure–function relationship. Expand
Human skeletal muscle biochemical diversity
TLDR
Trends suggest that distal muscles should have higher passive tension than proximal ones, and that titin size variability may potentially act to ‘tune’ the protein's mechanotransduction capability. Expand
Impact of vaginal parity and aging on the architectural design of pelvic floor muscles.
TLDR
Increased fiber length in more proximal pelvic floor muscles likely represents an adaptive response to the chronically increased load placed on these muscles by the displaced apical structures, presumably as a consequence of vaginal delivery. Expand
Architectural design of the pelvic floor is consistent with muscle functional subspecialization
TLDR
PFM design shows individual muscles demonstrating differential architecture, corresponding to specialized function in the pelvic floor, corresponding with muscle-force production and excursion. Expand
Architectural assessment of rhesus macaque pelvic floor muscles: comparison for use as a human model
TLDR
Overall, RM provides the closest architectural representation of human PFM complex among species examined; however, differences between individual PFMs should be taken into consideration. Expand
Mechanical Analysis of the Uterosacral Ligament: Swine vs. Human
TLDR
The swine holds promise as large animal model for studying the mechanical role of the USL in apical vaginal support and treatment of POP, and no differences in the peak strain during preconditioning tests, secant modulus of the pre-creep response, and strain at the end of creep tests were detected. Expand
Age-associated changes in the mechanical properties of human cadaveric pelvic floor muscles.
TLDR
Age-associated increase in PFM stiffness is predicted to negatively impact PFM function by diminishing muscle load-bearing, excursional, contractile, and regenerative capacity, thus predisposing older women to PFDs. Expand
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