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Embryonic Neurons Adapt to the Inhibitory Proteoglycan Aggrecan by Increasing Integrin Expression
The primary mediators of cell migration during development, wound healing and metastasis, are receptors of the integrin family. In the developing and regenerating nervous system, chondroitin sulfateExpand
Apical cell shape changes during Drosophila imaginal leg disc elongation: a novel morphogenetic mechanism.
Imaginal discs of Drosophila are simple epithelial tissues that undergo dramatic changes in shape during metamorphosis, including elongation to form adult appendages such as legs and wings. We haveExpand
Interactions of developing neurons with the extracellular matrix
The differentiation and morphogenesis of neural tissues involves a diversity of interactions between neural cells and their environment. Many potentially important interactions occur with theExpand
Spatially regulated translation in embryos: asymmetric expression of maternal Wnt-11 along the dorsal-ventral axis in Xenopus.
Transition from symmetry to asymmetry is a central theme in cell and developmental biology. In Xenopus embryos, dorsal-ventral asymmetry is initiated by a microtubule-dependent cytoplasmic rotationExpand
Sensory Neuron Subtypes Have Unique Substratum Preference and Receptor Expression before Target Innervation
The factors controlling the specification and subsequent differentiation of sensory neurons are poorly understood. Data from embryological manipulations suggest that either sensory neuron fates areExpand
Adult Neuronal Regeneration Induced by Transgenic Integrin Expression
  • M. Condic
  • Biology, Medicine
  • The Journal of Neuroscience
  • 1 July 2001
In a variety of adult CNS injury models, embryonic neurons exhibit superior regenerative performance when compared with adult neurons. It is unknown how young neurons extend axons in the injuredExpand
Removal of the basal lamina in vivo reveals growth cone-basal lamina adhesive interactions and axonal tension in grasshopper embryos
  • M. Condic, D. Bentley
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 1 August 1989
The Ti1 afferent neurons are the first cells to undergo axonogenesis in embryonic grasshopper limbs. The Ti1 growth cones migrate between the limb epithelium and its basal lamina. We haveExpand
Totipotency: what it is and what it is not.
  • M. Condic
  • Biology, Medicine
  • Stem cells and development
  • 15 April 2014
There is surprising confusion surrounding the concept of biological totipotency, both within the scientific community and in society at large. Increasingly, ethical objections to scientific researchExpand
Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth
Receptors of the integrin family are expressed by every cell type and are the primary means by which cells interact with the extracellular matrix. The control of integrin expression affects a wideExpand
Pioneer growth cone adhesion in vivo to boundary cells and neurons after enzymatic removal of basal lamina in grasshopper embryos
  • M. Condic, D. Bentley
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 1 August 1989
The Ti1 pioneer neurons of embryonic grasshopper limbs extend axons between the limb epithelium and its basal lamina. Their growth cones exhibit high affinity for both limb segment boundaries andExpand
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