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Demineralization–remineralization dynamics in teeth and bone
- E. A. Abou Neel, A. Aljabo, V. Mudera
- Materials ScienceInternational journal of nanomedicine
- 19 September 2016
Technologies discussed include composites with nano- and micron-sized inorganic minerals that can mimic mechanical properties of the tooth and bone in addition to promoting more natural repair of surrounding tissues.
Osteoinduction of bone grafting materials for bone repair and regeneration.
The effects of microporosity on osteoinduction of calcium phosphate bone graft substitute biomaterials.
Effect of increased strut porosity of calcium phosphate bone graft substitute biomaterials on osteoinduction.
- M. Coathup, K. Hing, G. Blunn
- Materials Science, MedicineJournal of biomedical materials research. Part A
- 1 June 2012
Increased bone formation was measured in the SiCaP with 30% strut porosity when compared with the nonsilicate CaP with the same morphology, indicating that silicate substitution may increase osteoinduction.
Augmentation of bone growth onto the acetabular cup surface using bone marrow stromal cells in total hip replacement surgery.
This study has clinical applications as greater bone contact at the cup surface will improve fixation and may decrease longer-term aseptic loosening by preventing wear debris-induced bone loss at the implant interface.
Osteoporosis and ageing affects the migration of stem cells and this is ameliorated by transfection with CXCR4
Osteoporosis and ageing affects the migration of stem cells and this is ameliorated by transfection with CXCR4, which could possibly enhance fracture healing in osteoporotic patients.
A comparison of bone remodelling around hydroxyapatite-coated, porous-coated and grit-blasted hip replacements retrieved at post-mortem.
- M. Coathup, G. Blunn, N. Flynn, C. Williams, N. Thomas
- MedicineThe Journal of bone and joint surgery. British…
HA coating increases the amount of ingrowth and attachment of bone and leads to a more even distribution of bone over the surface of the implant, which may have implications in reducing stress shielding and limiting osteolysis induced by wear particles.
Antimicrobial photodynamic therapy—a promising treatment for prosthetic joint infections
It is demonstrated that PDT is effective for killing bacteria that cause PJI.
Controlled laser texturing of titanium results in reliable osteointegration
- M. Coathup, G. Blunn, Lin Li
- Materials ScienceJournal of orthopaedic research : official…
- 1 April 2017
This study demonstrated that laser‐textured implants are a very promising technical development that warrants further research.
Long-term survival of cemented distal femoral endoprostheses with a hydroxyapatite-coated collar: a histological study and a radiographic follow-up.
- M. Coathup, V. Batta, G. Blunn
- MedicineThe Journal of bone and joint surgery. American…
- 4 September 2013
The use of cemented distal femoral massive bone tumor prostheses with a hydroxyapatite-coated collar located at the shoulder of the implant was followed by a low rate of revision due to aseptic loosening.