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Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
Summary Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic potential. Multiple DC subsets have been described, and it remains challenging to align them acrossExpand
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Coronavirus disease 2019 (COVID-19) pandemic and pregnancy
Abstract The current coronavirus disease 2019 (COVID-19) pneumonia pandemic, caused by the severe acute respiratory syndrome 2 (SARS-CoV-2) virus, is spreading globally at an accelerated rate,Expand
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A study on Singaporean women's acceptance of using mobile phones to seek health information
OBJECTIVE This paper is an exploratory study that investigates Singaporean women's acceptance of using mobile phones to seek health information. METHOD A mobile web containing health topics wasExpand
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Superior Osteogenic Capacity for Bone Tissue Engineering of Fetal Compared with Perinatal and Adult Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) from human adult bone marrow (haMSCs) represent a promising source for bone tissue engineering. However, their low frequencies and limited proliferation restrict theirExpand
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An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
The phenotypic transformation of well-differentiated epithelial carcinoma into a mesenchymal-like state provides cancer cells with the ability to disseminate locally and to metastasise. DifferentExpand
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Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2
During gestation the developing human fetus is exposed to a diverse range of potentially immune-stimulatory molecules including semi-allogeneic antigens from maternal cells, substances from ingestedExpand
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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer
Epithelial ovarian cancer (EOC) is hallmarked by a high degree of heterogeneity. To address this heterogeneity, a classification scheme was developed based on gene expression patterns of 1538Expand
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Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21
The 40-fold increase in childhood megakaryocyte-erythroid and B-cell leukemia in Down syndrome implicates trisomy 21 (T21) in perturbing fetal hematopoiesis. Here, we show that compared with primaryExpand
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An exploratory study of ageing women's perception on access to health informatics via a mobile phone-based intervention
OBJECTIVE This is an exploratory study examining the perceived attitudes and readiness of women aged 50 years or older on adopting a mobile phone-based intervention named as Infohealth in Singapore.Expand
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Sonographic diagnosis and successful medical management of an intramural ectopic pregnancy
We report a case of posterior wall intramural pregnancy in a 36‐year‐old primigravida at 6 weeks gestation. Sonographic examination showed a viable intramural pregnancy distorting the contour of theExpand
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