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Protein and peptide arrays: recent trends and new directions.
Microarrays of proteins and peptides make it possible the screening of thousands of binding events in a parallel and high throughput fashion; therefore they are emerging as a powerful tool forExpand
Digital Detection of Exosomes by Interferometric Imaging
Exosomes, which are membranous nanovesicles, are actively released by cells and have been attributed to roles in cell-cell communication, cancer metastasis, and early disease diagnostics. The smallExpand
Quantification of DNA and protein adsorption by optical phase shift.
A primary advantage of label-free detection methods over fluorescent measurements is its quantitative detection capability, since an absolute measure of adsorbed material facilitates kineticExpand
New adsorbed coatings for capillary electrophoresis
New acrylic polymers bearing oxirane groups were synthesized to be used in the production of coated capillaries. A fully automated coating procedure was devised based on the use of diluted waterExpand
Protein microarray technology: how far off is routine diagnostics?
The nature of protein microarray platforms is favorable for multiplexing, leading to the development of tools for personalised medicine and highly precise diagnostics. However, to date, only aExpand
Development of a high-sensitivity immunoassay for amyloid-beta 1-42 using a silicon microarray platform.
In this work, we present a highly sensitive immunoassay for the detection of the Alzheimer's disease (AD) biomarker amyloid-beta 1-42 (Aβ42) based on a label/label-free microarray platform thatExpand
Detection of allergen specific immunoglobulins by microarrays coupled to microfluidics
Allergen microarrays are under development for a component‐resolved diagnosis of Type I (IgE‐mediated) allergies. Here we report an improved microarray coupled to microfluidics for the detection ofExpand
Rapid capillary coating by epoxy‐poly‐(dimethylacrylamide): Performance in capillary zone electrophoresis of protein and polystyrene carboxylate
A fast and simple method for the internal coating of capillaries in capillary zone electrophoresis (CZE) is that with epoxy‐poly(dimethylacrylamide) (EPDMA). Duration of coating by that method is 30Expand
Multispot, label-free biodetection at a phantom plastic–water interface
Recognizing and quantifying specific biomolecules in aqueous samples are constantly needed in research and diagnostic laboratories. As the typical detection procedures are rather lengthy and involveExpand