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Nitric oxide and cancer: a review
- Sheetal Korde Choudhari, M. Chaudhary, Sachin Bagde, A. Gadbail, Vaishali Joshi
- World Journal of Surgical Oncology
- 30 May 2013
Various mechanisms by which NO acts in different cancers such as breast, cervical, gastric,colorectal, and head and neck cancers are addressed and its novel therapeutic applications for cancer prevention and treatment are discussed. Expand
Oxidative and antioxidative mechanisms in oral cancer and precancer: a review.
- Sheetal Choudhari, M. Chaudhary, A. Gadbail, Aparna Sharma, S. Tekade
- Chemistry, Medicine
- Oral oncology
This review is an attempt to understand the interesting correlation between ROS and RNS mediated cell damage and enzymatic and non-enzymatic defence mechanisms involved in oral cancer development and its progression and the use of antioxidants in Oral cancer prevention and treatment. Expand
Actual Proliferating Index and p53 protein expression as prognostic marker in odontogenic cysts.
The quantitative and qualitative differences of the proliferative activity and the p53 protein expression in sporadic KCOT may be associated with intrinsic growth potential that could play a role in its development and explain locally aggressive biological behaviour. Expand
Tumor angiogenesis in keratocystic odontogenic tumor assessed by using CD-105 antigen.
- A. Gadbail, A. Hande, +5 authors S. Gondivkar
- Medicine, Biology
- Journal of oral pathology & medicine : official…
- 1 March 2011
The result suggests that CD105 (endoglin) is strongly expressed in microvessels of KCOT compared with that in Dentigerous cyst and Normal oral mucosa, suggesting that angiogenesis may be associated with locally aggressive biological behavior of KCot. Expand
Co-expression of Ki-67 and p53 protein in ameloblastoma and keratocystic odontogenic tumor
- A. Gadbail, Rahul Krishnarao Patil, M. Chaudhary
- Acta odontologica Scandinavica
- 10 October 2012
The results suggest that the p53 protein expression does not necessarily imply an association with malignant disease and/or p53 gene mutation, but a tendency to be expressed in an increasing quantitative and qualitative manner, as the biologic behavior of odontogenic cyst or tumors becomes more aggressive. Expand
Evaluation of chemiluminescence, toluidine blue and histopathology for detection of high risk oral precancerous lesions: A cross-sectional study
The results indicate that toluidine blue retention test may be better suited than chemiluminescence to detect high-risk oral precancerous lesions in a high-prevalence and low-resource setting like India. Expand
Fibrosarcoma of the oral cavity.
- V. Wadhwan, M. Chaudhary, M. Gawande
- Indian journal of dental research : official…
- 1 April 2010
Fibrosarcoma has been defined as a malignant tumor of the fibroblasts that shows no other evidence of cellular differentiation and is capable of recurrence and metastasis. Fibrosarcomas are rare but… Expand
Enhanced Nitrosative and Oxidative Stress with Decreased Total Antioxidant Capacity in Patients with Oral Precancer and Oral Squamous Cell Carcinoma
It is conjecture that oxidative DNA damage, a vital phenomenon for carcinogenesis, occurs due to the interplay of ROS, RNS and TAC, as demonstrated by significantly low levels of TAC. Expand
Cytomorphometric analysis of buccal mucosa of tobacco chewers.
There is progressive decrease in cellular diameter, increase in nuclear diameter and increase in ratio of nuclear diameter to cellular diameter in smears from all tobacco users, as compared to normal subjects, indicating that there could be cause-effect relationship between tobacco and quantitative alterations. Expand
Evaluation of Prognostic Significance of Immunological Cells (Tissue Eosinophil and Mast Cell) Infiltration in Oral Squamous Cell Carcinoma
Quantitative assessment of eosinophils and mast cells are the most important aspects of the microscopic evaluation of OSCC, and it is concluded that infiltration of tissue eos inophil andmast cells are indicators of favourable prognosis in OSCC. Expand