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Rising Antimicrobial Resistance of Pseudomonas aeruginosa Isolated fromClinical Specimens in India
Isolates harboring MBL and ESBL+MBL genes were resistant to almost all antibiotics except Elores, which can be concluded that Elores was highly potent against MBL producing P. aeruginosa.
Incidence, prevalence and control of multidrug resistant (MDR) carbapenemase producing Acinetobacter baumanii in Indian intensive care units
Results of the present study revealed that Elores was the most active amongst commonly used antibiotics in ICU settings, which showed 93–96% susceptibility, therefore can be a potent antibacterial option for the treatment of infections caused by carbapenemase producing A. baumannii.
Protective role of ceftriaxone plus sulbactam with VRP1034 on oxidative stress, hematological and enzymatic parameters in cadmium toxicity induced rat model
The findings indicate that ceftriaxone plus sulbactam with VRP1034 acts as a potent free radical scavenger and exhibits metal chelating properties that reduce free radical mediated tissue injury and prevent dysfunction of hepatic and renal organs during metal intoxication.
A Novel High Performance Liquid Chromatographic Method for Simultaneous Determination of Ceftriaxone and Sulbactam in Sulbactomax
- S. Shrivastava, Rajkumar Singh, +4 authors M. Chaudhary
- Chemistry, MedicineInternational journal of biomedical science…
- 1 March 2009
An isocratic liquid chromatographic method with UV detection at 220 nm is described for simultaneous determination of ceftriaxone sodium and sulbactam sodium in Sulbactomax and offers symmetric peak shape, good resolution and reasonable retention time for both drugs.
A Novel Approach to Combat Acquired Multiple Resistance in Escherichia coli by using EDTA as Efflux Pump Inhibitor
There are a number of reports indicating antibiotic resistance because of efflux pump in bacteria is increasing significantly, and antibiotic efflux pumps are thought of as attractive therapeutic targets, where their inhibition can restore antibiotic activity.
Molecular Characterization and Antimicrobial Susceptibility Study of Acinetobacter baumannii Clinical Isolates from Middle East, African and Indian Patients
Acinetobacter species are aerobic gram-negative organism being responsible for various types of infections such as pneumonia, urinary tract infection and septicemia [1-4]. The Acenitobacter…
Clinical, microbial efficacy and tolerability of Elores, a novel antibiotic adjuvant entity in ESBL producing pathogens: Prospective randomized controlled clinical trial
Results of this study indicates that Elores is more safe and effective regimen in treating ESBL producing gram-negative and gram-positive pathogens in comparison to plain ceftriaxone.
EVALUATION OF HEAVY METALS IN TWO MAJOR INGREDIENTS OF AMPUCARE
The World Health Organization (WHO) estimates that 4 billion people or 80 percent of the world population, presently use herbal medicine for some aspect of primary health care and 25% of modern…
Molecular characterization and in vitro susceptibilities of β-lactamase producing Escherichia coli, Klebsiella species, Acinetobacter baumannii, Pseudomonas aeruginosa and Staphylococcus aureus to…
Results of the present study indicated that majority of the isolates was susceptible to CSE1034 and it could be a potent antibacterial agent for the treatment of severe bacterial infections caused by such organisms.
Role of CSE1034 in Escherichia coli Biofilm Destruction
It was found that, among the drugs used, CSE1034 was the most effective against all of the E. coli clinical isolates, and due to presence of 10 mM EDTA led to enhanced antibacterial, as well as biofilm destruction activities.