M. Castells

Publications247
h-index48
Citations7,841
Highly Influential Citations355
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Standards and standardization in mastocytosis: Consensus Statements on Diagnostics, Treatment Recommendations and Response Criteria
Although a classification for mastocytosis and diagnostic criteria are available, there remains a need to define standards for the application of diagnostic tests, clinical evaluations, and treatment… Expand
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International Consensus on drug allergy
When drug reactions resembling allergy occur, they are called drug hypersensitivity reactions (DHRs) before showing the evidence of either drug‐specific antibodies or T cells. DHRs may be allergic or… Expand
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Hypersensitivity reactions to chemotherapy: outcomes and safety of rapid desensitization in 413 cases.
BACKGROUND Hypersensitivity reactions (HSRs) to chemotherapeutic drugs, including mAbs, often require that the provoking medication be discontinued, thus raising a dilemma for the caregiver: further… Expand
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Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal
Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various organs are typically found in primary MC disorders also referred to as mastocytosis. However, increasing… Expand
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Hypersensitivity reactions to mAbs: 105 desensitizations in 23 patients, from evaluation to treatment.
BACKGROUND Rapid desensitization, a procedure for graded drug administration, allows for the safe readministration of a medication after certain types of hypersensitivity reactions (HSRs) and is… Expand
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Mastocytosis: current concepts in diagnosis and treatment
Abstract. Mastocytosis consists of a group of disorders characterized by a pathologic increase in mast cells in tissues including skin, bone marrow, liver, spleen, and lymph nodes. Mastocytosis is a… Expand
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Anaphylaxis During the Perioperative Period
Anesthesiologists use a myriad of drugs during the provision of an anesthetic. Many of these drugs have side effects that are dose related, and some lead to severe immune-mediated adverse reactions.… Expand
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Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European…
Cutaneous lesions in patients with mastocytosis are highly heterogeneous and encompass localized and disseminated forms. Although a classification and criteria for cutaneous mastocytosis (CM) have… Expand
  • 156
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Latex Allergy: An Update
The rate of latex sensitization has been increasing since its first recognition in 1979, and anesthesiologists encounter patients with a diagnosis of latex allergy more and more often (1). Latex is a… Expand
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General considerations on rapid desensitization for drug hypersensitivity – a consensus statement
To cite this article: Cernadas JR, Brockow K, Romano A, Aberer W, Torres MJ, Bircher A, Campi P, Sanz ML, Castells M, Demoly P, Pichler WJ, for the European Network of Drug Allergy and the EAACI… Expand
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