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- Publications
- Influence
Echinostome infection in green frogs (Rana clamitans) is stage and age dependent
- M. P. Holland, D. Skelly, M. Kashgarian, Susan R. Bolden, L. M. Harrison, M. Cappello
- Biology
- 1 April 2007
The increasing threat of emerging infectious diseases in both wildlife and humans has spurred interest in the causes of disease emergence, including the role of anthropogenic change. A prior field… Expand
Anticoagulant repertoire of the hookworm Ancylostoma caninum.
- P. Stassens, P. Bergum, +10 authors G. Vlasuk
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 5 March 1996
Hookworms are hematophagous nematodes that infect a wide range of mammalian hosts, including humans. There has been speculation for nearly a century as to the identity of the anticoagulant… Expand
A Leishmania Ortholog of Macrophage Migration Inhibitory Factor Modulates Host Macrophage Responses1
- Daniela Kamir, S. Zierow, +17 authors R. Bucala
- Biology, Medicine
- The Journal of Immunology
- 15 June 2008
Parasitic organisms have evolved specialized strategies to evade immune defense mechanisms. We describe herein an ortholog of the cytokine, macrophage migration inhibitory factor (MIF), which is… Expand
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
- Y. Cho, G. Crichlow, +9 authors E. Lolis
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 8 June 2010
AV411 (ibudilast; 3-isobutyryl-2-isopropylpyrazolo-[1,5-a]pyridine) is an antiinflammatory drug that was initially developed for the treatment of bronchial asthma but which also has been used for… Expand
Orthologs of macrophage migration inhibitory factor from parasitic nematodes.
- J. Vermeire, Y. Cho, E. Lolis, R. Bucala, M. Cappello
- Biology, Medicine
- Trends in parasitology
- 1 August 2008
Chronic helminth infections are associated with modulation of host cellular immune responses, presumably to prolong parasite survival within the mammalian host. This phenomenon is attributed, at… Expand
Teaching Treaties as (Un)Usual Narratives: Disrupting the Curricular Commonsense
- J. Tupper, M. Cappello
- Sociology
- 1 December 2008
Abstract This article examines the importance of treaty education for students living in a province entirely ceded through treaty. Specifically, we ask and attempt to answer the questions “Why teach… Expand
A novel family of anticoagulants from the saliva of Ixodes scapularis
- S. Narasimhan, R. Koski, +5 authors E. Fikrig
- Biology, Medicine
- Insect molecular biology
- 1 December 2002
Using biochemical and molecular approaches, we have identified a 9.8 kDa protein in the saliva of Ixodes scapularis that inhibits the intrinsic pathway of coagulation. The 9.8 kDa anticoagulant… Expand
Isolation and characterization of the tsetse thrombin inhibitor: a potent antithrombotic peptide from the saliva of Glossina morsitans morsitans.
- M. Cappello, P. Bergum, G. Vlasuk, B. Furmidge, D. Pritchard, S. Aksoy
- Biology, Medicine
- The American journal of tropical medicine and…
- 1 May 1996
A potent and specific inhibitor of the human coagulation protease thrombin was identified in salivary gland extracts of the tsetse fly, Glossina morsitans morsitans, an important vector of African… Expand
Epidemiology and Management of Infectious Diseases in International Adoptees
- T. Murray, M. Groth, C. Weitzman, M. Cappello
- Medicine
- Clinical Microbiology Reviews
- 1 July 2005
SUMMARY International adoptees represent a group of children with unique health care needs. Data from published studies, along with the recent experience of the Yale International Adoption Clinic,… Expand
Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.
- M. Cappello, G. Vlasuk, P. Bergum, S. Huang, P. Hotez
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 20 June 1995
Human hookworm infection is a major cause of gastrointestinal blood loss and iron deficiency anemia, affecting up to one billion people in the developing world. These soil-transmitted helminths cause… Expand