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Echinostome infection in green frogs (Rana clamitans) is stage and age dependent
The increasing threat of emerging infectious diseases in both wildlife and humans has spurred interest in the causes of disease emergence, including the role of anthropogenic change. A prior fieldExpand
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Anticoagulant repertoire of the hookworm Ancylostoma caninum.
Hookworms are hematophagous nematodes that infect a wide range of mammalian hosts, including humans. There has been speculation for nearly a century as to the identity of the anticoagulantExpand
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A Leishmania Ortholog of Macrophage Migration Inhibitory Factor Modulates Host Macrophage Responses1
Parasitic organisms have evolved specialized strategies to evade immune defense mechanisms. We describe herein an ortholog of the cytokine, macrophage migration inhibitory factor (MIF), which isExpand
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Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
AV411 (ibudilast; 3-isobutyryl-2-isopropylpyrazolo-[1,5-a]pyridine) is an antiinflammatory drug that was initially developed for the treatment of bronchial asthma but which also has been used forExpand
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Orthologs of macrophage migration inhibitory factor from parasitic nematodes.
Chronic helminth infections are associated with modulation of host cellular immune responses, presumably to prolong parasite survival within the mammalian host. This phenomenon is attributed, atExpand
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Teaching Treaties as (Un)Usual Narratives: Disrupting the Curricular Commonsense
Abstract This article examines the importance of treaty education for students living in a province entirely ceded through treaty. Specifically, we ask and attempt to answer the questions “Why teachExpand
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A novel family of anticoagulants from the saliva of Ixodes scapularis
Using biochemical and molecular approaches, we have identified a 9.8 kDa protein in the saliva of Ixodes scapularis that inhibits the intrinsic pathway of coagulation. The 9.8 kDa anticoagulantExpand
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Isolation and characterization of the tsetse thrombin inhibitor: a potent antithrombotic peptide from the saliva of Glossina morsitans morsitans.
A potent and specific inhibitor of the human coagulation protease thrombin was identified in salivary gland extracts of the tsetse fly, Glossina morsitans morsitans, an important vector of AfricanExpand
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Epidemiology and Management of Infectious Diseases in International Adoptees
SUMMARY International adoptees represent a group of children with unique health care needs. Data from published studies, along with the recent experience of the Yale International Adoption Clinic,Expand
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Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.
Human hookworm infection is a major cause of gastrointestinal blood loss and iron deficiency anemia, affecting up to one billion people in the developing world. These soil-transmitted helminths causeExpand
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