Oufti: an integrated software package for high‐accuracy, high‐throughput quantitative microscopy analysis
- Ahmad Paintdakhi, Bradley R. Parry, C. Jacobs-Wagner
- BiologyMolecular Microbiology
- 1 February 2016
Oufti provides computational solutions for tracking touching cells in confluent samples, handles various cell morphologies, offers algorithms for quantitative analysis of both diffraction and non‐diffraction‐limited fluorescence signals and is scalable for high‐throughput analysis of massive datasets, all with subpixel precision.
A Constant Size Extension Drives Bacterial Cell Size Homeostasis
- M. Campos, I. Surovtsev, C. Jacobs-Wagner
- BiologyCell
- 4 December 2014
Detailed structural and assembly model of the type II secretion pilus from sparse data
- M. Campos, M. Nilges, D. A. Cisneros, O. Francetic
- BiologyProceedings of the National Academy of Sciences
- 2 July 2010
The detailed, experimentally validated structure of the PulG pilus generated from crystallographic and electron microscopy data is described, supported by the conserved character of residues involved in key hydrophobic and electrostatic interactions within the major pseudopilin family.
O-Linked Glycosylation Ensures the Normal Conformation of the Autotransporter Adhesin Involved in Diffuse Adherence
- Marie-Ève Charbonneau, V. Girard, M. Mourez
- BiologyJournal of Bacteriology
- 19 October 2007
The results suggest that glycosylation is required to ensure a normal conformation of AIDA-I and may be only indirectly necessary for its cell-binding function.
Minor pseudopilin self‐assembly primes type II secretion pseudopilus elongation
- D. A. Cisneros, P. Bond, A. Pugsley, M. Campos, O. Francetic
- BiologyEMBO Journal
- 15 February 2012
It is proposed that PulI, PulJ and PulK self‐assembly is thermodynamically coupled to the initiation of pseudopilus assembly, possibly setting the assembly machinery in motion.
The type II secretion system - a dynamic fiber assembly nanomachine.
- M. Campos, D. A. Cisneros, M. Nivaskumar, O. Francetic
- BiologyResearch in Microbiology
- 1 July 2013
DNA-relay mechanism is sufficient to explain ParA-dependent intracellular transport and patterning of single and multiple cargos
- I. Surovtsev, M. Campos, C. Jacobs-Wagner
- BiologyProceedings of the National Academy of Sciences
- 31 October 2016
A simple model that considers only the known biochemical properties of the ParA and ParB proteins and the stochastic dynamics of chromosomal loci explains the spontaneous formation of propagating protein gradients, cargo oscillations, and equidistant patterns that are characteristic of ParA/B systems.
Mycofumigation by the Volatile Organic Compound-Producing Fungus Muscodor albus Induces Bacterial Cell Death through DNA Damage
- C. Alpha, M. Campos, C. Jacobs-Wagner, S. Strobel
- BiologyApplied and Environmental Microbiology
- 1 December 2014
The sensitivity of knockouts involved in the repair of specific DNA alkyl adducts suggests that the VOCs may induce alkylation, and evidence of DNA damage suggests that theseAdducts lead to breaks during DNA replication or transcription if not properly repaired.
Modeling pilus structures from sparse data.
- M. Campos, O. Francetic, M. Nilges
- BiologyJournal of Structural Biology
- 1 March 2011
...
...