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U‐serrated immunodeposition pattern differentiates type VII collagen targeting bullous diseases from other subepidermal bullous autoimmune diseases
Background Epidermolysis bullosa acquisita (EBA) can be differentiated from other subepidermal bullous diseases by sophisticated techniques such as immunoelectron microscopy, salt‐split skin antigen… Expand
Detection of immune deposits in skin lesions of patients with Wegener's granulomatosis
- R. Brons, M. C. de Jong, N. D. de Boer, C. Stegeman, C. Kallenberg, J. W. Tervaert
- Annals of the rheumatic diseases
- 1 December 2001
BACKGROUND Wegener's granulomatosis (WG) is considered a pauci-immune systemic vasculitis based on the absence of immune deposits in renal biopsies of patients with active disease. In animal models… Expand
180-kD bullous pemphigoid antigen (BP180) is deficient in generalized atrophic benign epidermolysis bullosa.
- M. Jonkman, M. C. de Jong, +6 authors A. Sonnenberg
- Chemistry, Medicine
- The Journal of clinical investigation
- 1 March 1995
Generalized atrophic benign epidermolysis bullosa (GABEB) is a form of nonlethal junctional epidermolysis bullosa characterized by universal alopecia and atrophy of the skin. We report a deficiency… Expand
Defined in situ enumeration of T6 and HLA-DR expressing epidermal Langerhans cells: morphologic and methodologic aspects.
- M. C. de Jong, R. Blanken, J. Nanninga, P. C. van Voorst Vader, S. Poppema
- Biology, Medicine
- The Journal of investigative dermatology
- 1 December 1986
An essential prerequisite for the in situ enumeration of epidermal Langerhans cells (LCs) is the unequivocal identification of the desired cell type. We have examined over 250 cryostat sections of… Expand
Enhanced diagnostic immunofluorescence using biopsies transported in saline
- R. Vodegel, M. C. de Jong, H. J. Meijer, Marijn B Weytingh, H. Pas, M. Jonkman
- BMC dermatology
- 27 August 2004
BackgroundThe demonstration of tissue-bound immunoreactants by direct immunofluorescence microscopy (DIF) is a valuable parameter in the diagnosis of various autoimmune and immunecomplex-mediated… Expand
Generalized atrophic benign epidermolysis bullosa. Either 180-kd bullous pemphigoid antigen or laminin-5 deficiency.
- M. Jonkman, M. C. de Jong, +7 authors L. Bruckner-Tuderman
- Archives of dermatology
- 1 February 1996
BACKGROUND Generalized atrophic benign epidermolysis bullosa (GABEB) is a form of nonlethal junctional epidermolysis bullosa, clinically characterized by generalized blistering after birth, atrophic… Expand
IgA-mediated epidermolysis bullosa acquisita: two cases and review of the literature.
- R. Vodegel, M. C. de Jong, H. Pas, M. Jonkman
- Journal of the American Academy of Dermatology
- 1 December 2002
We describe 2 adult patients with a subepidermal bullous dermatosis with exclusively linear IgA depositions along the epidermal basement membrane zone that were deposited in the sublamina densa zone… Expand
Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus?
Apoptotic cells are thought to play an essential role in the pathogenesis of systemic lupus erythematosus (SLE). We hypothesise that delayed or altered clearance of apoptotic cells after UV… Expand
Bullous pemphigoid and epidermolysis bullosa acquisita. Differentiation by fluorescence overlay antigen mapping.
BACKGROUND AND DESIGN From previous studies, we concluded that the fluorescence overlay antigen mapping (FOAM) technique could be of value to the differential diagnosis of the acquired subepidermal… Expand
Coexistence of IgA antibodies to desmogleins 1 and 3 in pemphigus vulgaris, pemphigus foliaceus and paraneoplastic pemphigus
- L. Mentink, M. C. de Jong, G. Kloosterhuis, J. Zuiderveen, M. Jonkman, H. Pas
- Medicine, Biology
- The British journal of dermatology
- 1 August 2004
Background Pemphigus is a bullous mucocutaneous autoimmune disease characterized by IgG autoantibodies to desmoglein (Dsg) 1 and/or Dsg3. Occasionally direct immunofluorescence of pemphigus skin… Expand