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The cannabinoid receptor agonist WIN 55,212-2 regulates glutamate transmission in rat cerebral cortex: an in vivo and in vitro study.
The effects of the cannabinoid receptor agonist WIN 55,212-2 on endogenous extracellular glutamate levels in the prefrontal cortex of the awake rat and in primary cultures of rat cerebral cortexExpand
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Effects of sarizotan on the corticostriatal glutamate pathways
The effects of sarizotan, a 5‐HT1A agonist with additional affinity for D3 and D4 receptors, have been studied on the corticostriatal glutamate pathways using dual‐probe microdialysis in the awakeExpand
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Prenatal exposure to the CB1 receptor agonist WIN 55,212-2 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring.
The aim of this study was to investigate whether prenatal exposure to the cannabinoid CB1 receptor agonist WIN 55,212-2 (WIN) at a daily dose devoid of overt signs of toxicity and/or grossExpand
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Differential effects of acute and short‐term lithium administration on dialysate glutamate and GABA levels in the frontal cortex of the conscious rat
In the present study, we employed in vivo microdialysis in the frontal cortex of the awake rat to investigate the effects of acute and short‐term (twice daily, 3 days) lithium chloride administrationExpand
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Neurotensin enhances endogenous extracellular glutamate levels in primary cultures of rat cortical neurons: involvement of neurotensin receptor in NMDA induced excitotoxicity.
Primary cultures of cortical neurons were employed to investigate the modulatory effects of neurotensin on glutamate excitotoxicity and the possible neuroprotective actions of the neurotensinExpand
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Developmental exposure to methylmercury elicits early cell death in the cerebral cortex and long-term memory deficits in the rat
Experiments were performed to assess the neurotoxic effects induced by prenatal acute treatment with methylmercury on cortical neurons. To this purpose, primary neuronal cultures were obtained fromExpand
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Receptor–receptor interactions as studied with microdialysis. Focus on NTR/D2 interactions in the basal ganglia
Summary.Using mono and dualprobe(s) microdialysis in the basal ganglia of the freely moving rat evidence has been obtained that neurotensin (NT) in threshold concentrations can counteract the D2Expand
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Differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: Possible relevance for wakefulness and depression
The present in vivo microdialysis study evaluates the possible existence of a differential regulation of serotonergic transmission by the antinarcoleptic drug modafinilExpand
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Nigral neurotensin receptor regulation of nigral glutamate and nigroventral thalamic GABA transmission: a dual-probe microdialysis study in intact conscious rat brain
Dual-probe microdialysis in the awake rat was employed to investigate the effects of intranigral perfusion with the tridecapeptide neurotensin on local dialysate glutamate and GABA levels in theExpand
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Modafinil enhances the increase of extracellular serotonin levels induced by the antidepressant drugs fluoxetine and imipramine: A dual probe microdialysis study in awake rat
In view of a postulated role of the vigilance‐promoting drug modafinil in depression, the interaction of modafinil and two classical antidepressant drugs, fluoxetine and imipramine, were studied inExpand
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